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CATH Superfamily 2.70.170.10

Neurotransmitter-gated ion-channel ligand-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Neurotransmitter-gated ion-channel ligand-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 55: Proton-gated ion channel subunit pbo-6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular ligand-gated ion channel activity GO:0005230
Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.
 2 G5ECT0 (/IDA) Q19351 (/IDA)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Lipid transport involved in lipid storage GO:0010877
The directed movement of lipids into cells that is part of their accumulation and maintenance.
 1 G5ECT0 (/IMP)
Defecation GO:0030421
The expulsion of feces from the rectum.
 1 G5ECT0 (/IMP)
Positive regulation of striated muscle contraction GO:0045989
Any process that activates or increases the frequency, rate or extent of striated muscle contraction.
 1 G5ECT0 (/IMP)
Positive regulation of intestinal lipid absorption GO:1904731
Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption.
 1 G5ECT0 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.