The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cadherins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 33: FAT atypical cadherin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 A0A087WRT4 (/IPI) A0A1L1SQU7 (/IPI) F2Z4A3 (/IPI) P33450 (/IPI) P33450 (/IPI) P33450 (/IPI) P33450 (/IPI) Q14517 (/IPI) Q9QXA3 (/IPI) Q9WU10 (/IPI)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
4 P33450 (/IDA) P33450 (/IDA) P33450 (/IDA) P33450 (/IDA)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
4 P33450 (/IPI) P33450 (/IPI) P33450 (/IPI) P33450 (/IPI)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q9VW71 (/ISM)
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
1 Q9WU10 (/IPI)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 Q9VW71 (/IPI)
Cell adhesion molecule binding GO:0050839
Interacting selectively and non-covalently with a cell adhesion molecule.
1 Q9VW71 (/IPI)

There are 83 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
8 A0A087WRT4 (/IMP) A0A1L1SQU7 (/IMP) F2Z4A3 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) Q9QXA3 (/IMP)
Cell morphogenesis involved in differentiation GO:0000904
The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
5 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) Q8BNA6 (/IMP)
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
4 P33450 (/IGI) P33450 (/IGI) P33450 (/IGI) P33450 (/IGI)
Establishment of planar polarity GO:0001736
Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Establishment of imaginal disc-derived wing hair orientation GO:0001737
Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Epithelial cell morphogenesis GO:0003382
The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.
4 A0A087WRT4 (/IMP) A0A1L1SQU7 (/IMP) F2Z4A3 (/IMP) Q9QXA3 (/IMP)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
4 A0A087WRT4 (/IMP) A0A1L1SQU7 (/IMP) F2Z4A3 (/IMP) Q9QXA3 (/IMP)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157
The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
4 P33450 (/IPI) P33450 (/IPI) P33450 (/IPI) P33450 (/IPI)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
4 A0A087WRT4 (/IMP) A0A1L1SQU7 (/IMP) F2Z4A3 (/IMP) Q9QXA3 (/IMP)
Establishment of tissue polarity GO:0007164
Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Imaginal disc growth GO:0007446
The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Imaginal disc pattern formation GO:0007447
The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Tissue development GO:0009888
The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Establishment or maintenance of polarity of larval imaginal disc epithelium GO:0016336
Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
4 P33450 (/IDA) P33450 (/IDA) P33450 (/IDA) P33450 (/IDA)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
4 P33450 (/NAS) P33450 (/NAS) P33450 (/NAS) P33450 (/NAS)
Peptide cross-linking GO:0018149
The formation of a covalent cross-link between or within protein chains.
4 P33450 (/IPI) P33450 (/IPI) P33450 (/IPI) P33450 (/IPI)
Regulation of protein localization GO:0032880
Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Regulation of tube length, open tracheal system GO:0035159
Ensuring that a tube in an open tracheal system is of the correct length.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Pupal development GO:0035209
The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Wing disc development GO:0035220
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
4 P33450 (/IGI) P33450 (/IGI) P33450 (/IGI) P33450 (/IGI)
Positive regulation of hippo signaling GO:0035332
Any process that activates or increases the frequency, rate or extent of hippo signaling.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
4 P33450 (/IGI) P33450 (/IGI) P33450 (/IGI) P33450 (/IGI)
Regulation of growth GO:0040008
Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Establishment of ommatidial planar polarity GO:0042067
The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.
4 P33450 (/IGI) P33450 (/IGI) P33450 (/IGI) P33450 (/IGI)
Establishment of ommatidial planar polarity GO:0042067
The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Cell-cell adhesion mediated by cadherin GO:0044331
The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.
4 P33450 (/IDA) P33450 (/IDA) P33450 (/IDA) P33450 (/IDA)
Establishment or maintenance of epithelial cell apical/basal polarity GO:0045197
Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
4 A0A087WRT4 (/IMP) A0A1L1SQU7 (/IMP) F2Z4A3 (/IMP) Q9QXA3 (/IMP)
Establishment of epithelial cell apical/basal polarity GO:0045198
The specification and formation of the apicobasal polarity of an epithelial cell.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Equator specification GO:0045317
The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Regulation of imaginal disc growth GO:0045570
Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Negative regulation of imaginal disc growth GO:0045571
Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Negative regulation of growth GO:0045926
Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
4 P33450 (/IGI) P33450 (/IGI) P33450 (/IGI) P33450 (/IGI)
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Establishment of body hair planar orientation GO:0048105
Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Camera-type eye morphogenesis GO:0048593
The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
4 A0A087WRT4 (/IMP) A0A1L1SQU7 (/IMP) F2Z4A3 (/IMP) Q9QXA3 (/IMP)
Wnt signaling pathway, planar cell polarity pathway GO:0060071
The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity.
4 P33450 (/TAS) P33450 (/TAS) P33450 (/TAS) P33450 (/TAS)
Microtubule cytoskeleton organization involved in establishment of planar polarity GO:0090176
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Protein localization involved in establishment of planar polarity GO:0090251
Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.
4 P33450 (/IMP) P33450 (/IMP) P33450 (/IMP) P33450 (/IMP)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
3 Q5F226 (/ISS) Q9NYQ8 (/ISS) Q9VW71 (/ISS)
Cartilage morphogenesis GO:0060536
The process in which the anatomical structures of cartilage are generated and organized.
3 A0A2R8QAL3 (/IMP) F1QA09 (/IMP) X1WCY4 (/IMP)
Epithelial cell migration GO:0010631
The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.
2 O88277 (/ISS) Q5F226 (/ISS)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
2 Q14517 (/ISS) Q9WU10 (/ISS)
Cell-substrate adhesion GO:0031589
The attachment of a cell to the underlying substrate via adhesion molecules.
2 O88277 (/ISS) Q5F226 (/ISS)
Neuron migration GO:0001764
The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
1 Q8BNA6 (/IMP)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
1 Q14517 (/ISS)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
1 Q14517 (/TAS)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
1 O88277 (/IDA)
Homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156
The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
1 Q5F226 (/ISO)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
1 Q14517 (/ISS)
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
1 Q14517 (/TAS)
Growth of a germarium-derived egg chamber GO:0007295
Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster.
1 Q9VW71 (/IMP)
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
1 Q9VW71 (/IMP)
Salivary gland development GO:0007431
The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.
1 Q9VW71 (/IMP)
Foregut morphogenesis GO:0007440
The process in which the anatomical structures of the foregut are generated and organized.
1 Q9VW71 (/IMP)
Hindgut morphogenesis GO:0007442
The process in which the anatomical structures of the hindgut are generated and organized.
1 Q9VW71 (/IMP)
Anatomical structure morphogenesis GO:0009653
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
1 Q14517 (/TAS)
Epithelial cell migration GO:0010631
The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.
1 Q9NYQ8 (/IDA)
Epithelial cell migration GO:0010631
The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.
1 Q9NYQ8 (/IMP)
Epithelial cell migration GO:0010631
The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.
1 Q5F226 (/ISO)
Retina layer formation GO:0010842
The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.
1 Q8BNA6 (/IGI)
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules GO:0016339
The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
1 Q9VW71 (/ISS)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
1 Q9QXA3 (/IMP)
Establishment or maintenance of actin cytoskeleton polarity GO:0030950
Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures.
1 Q9VW71 (/IMP)
Cell-substrate adhesion GO:0031589
The attachment of a cell to the underlying substrate via adhesion molecules.
1 Q9NYQ8 (/IDA)
Cell-substrate adhesion GO:0031589
The attachment of a cell to the underlying substrate via adhesion molecules.
1 Q5F226 (/ISO)
Establishment of planar polarity of follicular epithelium GO:0042247
Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates.
1 Q9VW71 (/IMP)
Cell-cell adhesion mediated by cadherin GO:0044331
The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.
1 Q9VW71 (/ISM)
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 Q9VW71 (/HMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 Q9VW71 (/IMP)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 Q9VW71 (/HMP)
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
1 Q9VW71 (/IMP)
Centripetally migrating follicle cell migration GO:0060269
The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte.
1 Q9VW71 (/IMP)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
1 Q14517 (/ISS)
Protein localization to cell leading edge GO:1902463
A process in which a protein is transported to, or maintained in, a location within a cell leading edge.
1 Q9VW71 (/IMP)
Negative regulation of dendrite development GO:2000171
Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.
1 Q8BNA6 (/IMP)

There are 30 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
6 A0A087WRT4 (/IDA) A0A1L1SQU7 (/IDA) F2Z4A3 (/IDA) Q14517 (/IDA) Q9QXA3 (/IDA) Q9VW71 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 A0A087WRT4 (/ISO) A0A1L1SQU7 (/ISO) F2Z4A3 (/ISO) Q9QXA3 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 A0A087WRT4 (/ISO) A0A1L1SQU7 (/ISO) F2Z4A3 (/ISO) Q9QXA3 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P33450 (/TAS) P33450 (/TAS) P33450 (/TAS) P33450 (/TAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 P33450 (/IDA) P33450 (/IDA) P33450 (/IDA) P33450 (/IDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 P33450 (/NAS) P33450 (/NAS) P33450 (/NAS) P33450 (/NAS)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
4 A0A087WRT4 (/ISO) A0A1L1SQU7 (/ISO) F2Z4A3 (/ISO) Q9QXA3 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
4 P33450 (/TAS) P33450 (/TAS) P33450 (/TAS) P33450 (/TAS)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
4 A0A087WRT4 (/IDA) A0A1L1SQU7 (/IDA) F2Z4A3 (/IDA) Q9QXA3 (/IDA)
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
4 P33450 (/IDA) P33450 (/IDA) P33450 (/IDA) P33450 (/IDA)
Lamellipodium GO:0030027
A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
4 A0A087WRT4 (/IDA) A0A1L1SQU7 (/IDA) F2Z4A3 (/IDA) Q9QXA3 (/IDA)
Cell junction GO:0030054
A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
4 A0A087WRT4 (/IDA) A0A1L1SQU7 (/IDA) F2Z4A3 (/IDA) Q9QXA3 (/IDA)
Filopodium GO:0030175
Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
4 A0A087WRT4 (/IDA) A0A1L1SQU7 (/IDA) F2Z4A3 (/IDA) Q9QXA3 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
4 A0A087WRT4 (/ISO) A0A1L1SQU7 (/ISO) F2Z4A3 (/ISO) Q9QXA3 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q14517 (/IDA) Q9WU10 (/IDA)
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
2 Q14517 (/IDA) Q9WU10 (/IDA)
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
2 O88277 (/ISS) Q5F226 (/ISS)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 Q14517 (/IDA) Q9WU10 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 Q14517 (/HDA) Q9NYQ8 (/HDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9VW71 (/ISS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q14517 (/TAS)
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
1 Q9NYQ8 (/IDA)
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
1 Q5F226 (/ISO)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 Q14517 (/HDA)
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
1 Q9VW71 (/IDA)
Basal plasma membrane GO:0009925
The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
1 Q9VW71 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 Q8BNA6 (/IDA)
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
1 Q9WU10 (/IDA)
Cell trailing edge GO:0031254
The area of a motile cell opposite to the direction of movement.
1 Q9VW71 (/IDA)
Actin-based cell projection GO:0098858
A cell projection supported by an assembly of actin filaments, and which lacks microtubules.
1 Q9VW71 (/IDA)