The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Kinesin-like protein Kif23, Arf6-interacting domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Kinesin-like protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
4 G5EC43 (/IDA) G5EG83 (/IDA) Q8MQ03 (/IDA) Q8MQ04 (/IDA)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
4 G5EC43 (/IPI) G5EG83 (/IPI) Q8MQ03 (/IPI) Q8MQ04 (/IPI)
Microtubule motor activity GO:0003777
Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
3 G5EC43 (/IDA) Q8MQ03 (/IDA) Q8MQ04 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 G5EG83 (/IPI) Q8MQ03 (/IPI) Q8MQ04 (/IPI)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
3 G5EC43 (/ISS) Q8MQ03 (/ISS) Q8MQ04 (/ISS)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
3 G5EC43 (/ISS) Q8MQ03 (/ISS) Q8MQ04 (/ISS)
ATP-dependent microtubule motor activity, plus-end-directed GO:0008574
Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP.
3 G5EC43 (/ISS) Q8MQ03 (/ISS) Q8MQ04 (/ISS)
ATP-dependent microtubule motor activity, plus-end-directed GO:0008574
Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP.
1 G5EG83 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 G5EG83 (/IPI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule-based movement GO:0007018
A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
4 G5EC43 (/IDA) G5EG83 (/IDA) Q8MQ03 (/IDA) Q8MQ04 (/IDA)
Regulation of actomyosin contractile ring contraction GO:0031991
Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.
4 G5EC43 (/IGI) G5EG83 (/IGI) Q8MQ03 (/IGI) Q8MQ04 (/IGI)
Regulation of actomyosin contractile ring contraction GO:0031991
Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.
4 G5EC43 (/IMP) G5EG83 (/IMP) Q8MQ03 (/IMP) Q8MQ04 (/IMP)
Pronuclear migration GO:0035046
The directed movement of the male and female pronuclei towards each other prior to their fusion.
4 G5EC43 (/IGI) G5EG83 (/IGI) Q8MQ03 (/IGI) Q8MQ04 (/IGI)
Polar body extrusion after meiotic divisions GO:0040038
The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes.
4 G5EC43 (/IMP) G5EG83 (/IMP) Q8MQ03 (/IMP) Q8MQ04 (/IMP)
Mitotic spindle midzone assembly GO:0051256
The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.
4 G5EC43 (/IMP) G5EG83 (/IMP) Q8MQ03 (/IMP) Q8MQ04 (/IMP)
Meiotic spindle midzone assembly GO:0051257
The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.
4 G5EC43 (/IMP) G5EG83 (/IMP) Q8MQ03 (/IMP) Q8MQ04 (/IMP)
Mitotic sister chromatid segregation GO:0000070
The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.
1 G5EG83 (/IGI)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
4 G5EC43 (/IDA) G5EG83 (/IDA) Q8MQ03 (/IDA) Q8MQ04 (/IDA)
Midbody GO:0030496
A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
4 G5EC43 (/IDA) G5EG83 (/IDA) Q8MQ03 (/IDA) Q8MQ04 (/IDA)
Cleavage furrow GO:0032154
The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
4 G5EC43 (/IDA) G5EG83 (/IDA) Q8MQ03 (/IDA) Q8MQ04 (/IDA)
Spindle midzone GO:0051233
The area in the center of the spindle where the spindle microtubules from opposite poles overlap.
4 G5EC43 (/IDA) G5EG83 (/IDA) Q8MQ03 (/IDA) Q8MQ04 (/IDA)
Mitotic spindle midzone GO:1990023
The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.
4 G5EC43 (/IDA) G5EG83 (/IDA) Q8MQ03 (/IDA) Q8MQ04 (/IDA)
Centralspindlin complex GO:0097149
A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).
1 Q8MQ04 (/IDA)