The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Extracellular matrix protein FRAS1 isoform 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
2 F1RYS0 (/RCA) Q80T14 (/RCA)
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
1 Q86XX4 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q80T14 (/IPI)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoderm development GO:0007492
The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.
9 A0A0R4IQJ3 (/IMP) A0A2R8Q1V0 (/IMP) A0A2R8QDV4 (/IMP) A0A2R8QFB7 (/IMP) A0A2R8QSM6 (/IMP) A2BHG4 (/IMP) B6IDE3 (/IMP) D7PS88 (/IMP) F1Q633 (/IMP)
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
9 A0A0R4IQJ3 (/IGI) A0A2R8Q1V0 (/IGI) A0A2R8QDV4 (/IGI) A0A2R8QFB7 (/IGI) A0A2R8QSM6 (/IGI) A2BHG4 (/IGI) B6IDE3 (/IGI) D7PS88 (/IGI) F1Q633 (/IGI)
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
9 A0A0R4IQJ3 (/IMP) A0A2R8Q1V0 (/IMP) A0A2R8QDV4 (/IMP) A0A2R8QFB7 (/IMP) A0A2R8QSM6 (/IMP) A2BHG4 (/IMP) B6IDE3 (/IMP) D7PS88 (/IMP) F1Q633 (/IMP)
Fin development GO:0033333
The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.
9 A0A0R4IQJ3 (/IMP) A0A2R8Q1V0 (/IMP) A0A2R8QDV4 (/IMP) A0A2R8QFB7 (/IMP) A0A2R8QSM6 (/IMP) A2BHG4 (/IMP) B6IDE3 (/IMP) D7PS88 (/IMP) F1Q633 (/IMP)
Fin morphogenesis GO:0033334
The process in which the anatomical structures of a fin are generated and organized.
9 A0A0R4IQJ3 (/IMP) A0A2R8Q1V0 (/IMP) A0A2R8QDV4 (/IMP) A0A2R8QFB7 (/IMP) A0A2R8QSM6 (/IMP) A2BHG4 (/IMP) B6IDE3 (/IMP) D7PS88 (/IMP) F1Q633 (/IMP)
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
9 A0A0R4IQJ3 (/IMP) A0A2R8Q1V0 (/IMP) A0A2R8QDV4 (/IMP) A0A2R8QFB7 (/IMP) A0A2R8QSM6 (/IMP) A2BHG4 (/IMP) B6IDE3 (/IMP) D7PS88 (/IMP) F1Q633 (/IMP)
Basement membrane organization GO:0071711
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
9 A0A0R4IQJ3 (/IMP) A0A2R8Q1V0 (/IMP) A0A2R8QDV4 (/IMP) A0A2R8QFB7 (/IMP) A0A2R8QSM6 (/IMP) A2BHG4 (/IMP) B6IDE3 (/IMP) D7PS88 (/IMP) F1Q633 (/IMP)
Morphogenesis of an epithelium GO:0002009
The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
1 Q80T14 (/IMP)
Metanephros morphogenesis GO:0003338
The process in which the anatomical structures of the metanephros are generated and organized.
1 Q80T14 (/IMP)
Cell adhesion GO:0007155
The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
1 P0C091 (/NAS)
Protein transport GO:0015031
The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q80T14 (/IMP)
Embryonic limb morphogenesis GO:0030326
The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
1 Q80T14 (/IMP)
Skin development GO:0043588
The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
1 Q80T14 (/IMP)
Roof of mouth development GO:0060021
The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities.
1 Q80T14 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
2 Q5H8B9 (/IDA) Q80T14 (/IDA)
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
2 P0C091 (/ISS) Q86XX4 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P0C091 (/HDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
1 Q80T14 (/HDA)