The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Superoxide dismutase, copper/zinc binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Superoxide dismutase [Cu-Zn]

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 33 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Superoxide dismutase activity GO:0004784
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
42 H6BDU4 (/ISS) O46412 (/ISS) P00442 (/ISS) P00443 (/ISS) P00443 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS) P09670 (/ISS)
(32 more)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
34 H6BDU4 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS)
(24 more)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
34 H6BDU4 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS)
(24 more)
Protein phosphatase 2B binding GO:0030346
Interacting selectively and non-covalently with the enzyme protein phosphatase 2B.
33 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(23 more)
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
33 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(23 more)
Superoxide dismutase activity GO:0004784
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
26 A1Z8K9 (/IDA) C0HK70 (/IDA) C1BFL3 (/IDA) O59924 (/IDA) O59924 (/IDA) O59924 (/IDA) O73872 (/IDA) O73872 (/IDA) P00441 (/IDA) P00441 (/IDA)
(16 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
19 P00441 (/IPI) P00441 (/IPI) P00441 (/IPI) P00441 (/IPI) P00441 (/IPI) P00442 (/IPI) P00445 (/IPI) P00445 (/IPI) P00445 (/IPI) P00445 (/IPI)
(9 more)
Superoxide dismutase activity GO:0004784
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
11 A1Z8K9 (/IMP) P07632 (/IMP) P08228 (/IMP) P28758 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) Q55GQ5 (/IMP)
(1 more)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
6 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00442 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
6 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00442 (/IDA)
Protein phosphatase 2B binding GO:0030346
Interacting selectively and non-covalently with the enzyme protein phosphatase 2B.
6 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P07632 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
6 P00441 (/IPI) P00441 (/IPI) P00441 (/IPI) P00441 (/IPI) P00441 (/IPI) Q8WRF5 (/IPI)
Antioxidant activity GO:0016209
Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
5 P61851 (/NAS) P61851 (/NAS) P61851 (/NAS) P61851 (/NAS) P61851 (/NAS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
5 P61851 (/IPI) P61851 (/IPI) P61851 (/IPI) P61851 (/IPI) P61851 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
5 P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS)
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
5 P00441 (/IPI) P00441 (/IPI) P00441 (/IPI) P00441 (/IPI) P00441 (/IPI)
Superoxide dismutase activity GO:0004784
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
4 P08228 (/TAS) P24704 (/TAS) P24704 (/TAS) P24704 (/TAS)
Superoxide dismutase activity GO:0004784
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
3 B2LYR9 (/NAS) B2LYS0 (/NAS) D2D329 (/NAS)
Superoxide dismutase activity GO:0004784
Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
1 P08228 (/ISO)
Ubiquitin-protein transferase activity GO:0004842
Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
1 P00442 (/ISS)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
1 P07632 (/IMP)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
1 P08228 (/ISO)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
1 P07632 (/TAS)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 P08228 (/ISO)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P07632 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P08228 (/ISO)
Protein phosphatase 2B binding GO:0030346
Interacting selectively and non-covalently with the enzyme protein phosphatase 2B.
1 P08228 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P08228 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P00442 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 H6BDU4 (/ISS)
Rac GTPase binding GO:0048365
Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
1 P08228 (/ISO)
Chaperone binding GO:0051087
Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
1 P08228 (/ISO)

There are 203 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
42 H6BDU4 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P00443 (/ISS) P00443 (/ISS) P04178 (/ISS)
(32 more)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
38 O46412 (/ISS) P00442 (/ISS) P00443 (/ISS) P00443 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P09670 (/ISS)
(28 more)
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
37 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(27 more)
Hydrogen peroxide biosynthetic process GO:0050665
The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
37 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(27 more)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Retina homeostasis GO:0001895
A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Myeloid cell homeostasis GO:0002262
The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Glutathione metabolic process GO:0006749
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Regulation of blood pressure GO:0008217
Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Transmission of nerve impulse GO:0019226
The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Peripheral nervous system myelin maintenance GO:0032287
The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Response to axon injury GO:0048678
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Neurofilament cytoskeleton organization GO:0060052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Relaxation of vascular smooth muscle GO:0060087
A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Auditory receptor cell stereocilium organization GO:0060088
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
36 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS)
(26 more)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
33 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(23 more)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
33 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(23 more)
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
33 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(23 more)
Regulation of mitochondrial membrane potential GO:0051881
Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
33 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(23 more)
Response to superoxide GO:0000303
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
32 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(22 more)
Positive regulation of cytokine production GO:0001819
Any process that activates or increases the frequency, rate or extent of production of a cytokine.
32 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(22 more)
Cell aging GO:0007569
An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).
32 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(22 more)
Negative regulation of cholesterol biosynthetic process GO:0045541
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
32 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(22 more)
Heart contraction GO:0060047
The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
31 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(21 more)
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
10 P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P08228 (/IMP) Q55GQ5 (/IMP)
Cellular zinc ion homeostasis GO:0006882
Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.
9 P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P28758 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
9 A1Z8K9 (/IMP) P07632 (/IMP) P08228 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) Q7JR71 (/IMP)
Age-dependent response to reactive oxygen species involved in chronological cell aging GO:0001320
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.
8 P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP)
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
8 P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
8 P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0036091
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
8 P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
8 P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
8 P00445 (/IPI) P00445 (/IPI) P00445 (/IPI) P00445 (/IPI) P00445 (/IPI) P00445 (/IPI) P00445 (/IPI) P00445 (/IPI)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
8 P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP)
Negative regulation of cellular respiration GO:1901856
Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration.
8 P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP) P00445 (/IMP)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
7 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00442 (/IDA) P07632 (/IDA)
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
6 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P07632 (/IDA)
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
6 P00441 (/IC) P00441 (/IC) P00441 (/IC) P00441 (/IC) P00441 (/IC) P28758 (/IC)
Hydrogen peroxide biosynthetic process GO:0050665
The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
6 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P07632 (/IDA)
Response to superoxide GO:0000303
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Age-dependent response to oxidative stress GO:0001306
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, where the change varies according to the age of the cell or organism.
5 P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP)
Positive regulation of cytokine production GO:0001819
Any process that activates or increases the frequency, rate or extent of production of a cytokine.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Placenta development GO:0001890
The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
5 P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS)
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
5 P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 P07632 (/TAS) P24704 (/TAS) P24704 (/TAS) P24704 (/TAS) Q9FK60 (/TAS)
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
5 P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
5 P61851 (/TAS) P61851 (/TAS) P61851 (/TAS) P61851 (/TAS) P61851 (/TAS)
Cell aging GO:0007569
An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).
5 P00441 (/IMP) P00441 (/IMP) P00441 (/IMP) P00441 (/IMP) P00441 (/IMP)
Anterograde axonal transport GO:0008089
The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.
5 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS)
Retrograde axonal transport GO:0008090
The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.
5 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
5 P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
5 P61851 (/TAS) P61851 (/TAS) P61851 (/TAS) P61851 (/TAS) P61851 (/TAS)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Positive regulation of superoxide anion generation GO:0032930
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Regulation of T cell differentiation in thymus GO:0033081
Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.
5 P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 P07632 (/IEP) P24704 (/IEP) P24704 (/IEP) P24704 (/IEP) Q9HEY7 (/IEP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 O59924 (/IMP) O59924 (/IMP) O59924 (/IMP) Q6FWL5 (/IMP) Q6FWL5 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
5 P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS)
Interleukin-12-mediated signaling pathway GO:0035722
A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
5 P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
5 P00441 (/IC) P00441 (/IC) P00441 (/IC) P00441 (/IC) P00441 (/IC)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Negative regulation of cholesterol biosynthetic process GO:0045541
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Regulation of organ growth GO:0046620
Any process that modulates the frequency, rate or extent of growth of an organ of an organism.
5 P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS)
Regulation of synaptic plasticity GO:0048167
A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
5 P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP)
Thymus development GO:0048538
The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.
5 P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS)
Regulation of mitochondrial membrane potential GO:0051881
Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
5 P00441 (/IMP) P00441 (/IMP) P00441 (/IMP) P00441 (/IMP) P00441 (/IMP)
Heart contraction GO:0060047
The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902177
Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.
5 P00441 (/IMP) P00441 (/IMP) P00441 (/IMP) P00441 (/IMP) P00441 (/IMP)
Regulation of autophagy of mitochondrion GO:1903146
Any process that modulates the frequency, rate or extent of mitochondrion degradation by an autophagic process.
5 P61851 (/IGI) P61851 (/IGI) P61851 (/IGI) P61851 (/IGI) P61851 (/IGI)
Regulation of terminal button organization GO:2000331
Any process that modulates the frequency, rate or extent of terminal button organization.
5 P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP) P61851 (/IMP)
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
4 A1Z8K9 (/IMP) P07632 (/IMP) P08228 (/IMP) Q7JR71 (/IMP)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
4 P07632 (/IEP) P24704 (/IEP) P24704 (/IEP) P24704 (/IEP)
Cellular response to ozone GO:0071457
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.
4 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP) Q9FK60 (/IEP)
Cellular response to salt stress GO:0071472
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
4 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP) Q9FK60 (/IEP)
Cellular response to light intensity GO:0071484
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
4 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP) Q9FK60 (/IEP)
Cellular response to UV-B GO:0071493
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
4 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP) Q9FK60 (/IEP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
3 O59924 (/IMP) O59924 (/IMP) O59924 (/IMP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
3 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP)
Response to iron ion GO:0010039
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
3 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP)
Response to ozone GO:0010193
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.
3 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
3 O59924 (/IMP) O59924 (/IMP) O59924 (/IMP)
Gene silencing by miRNA GO:0035195
Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of the RNA (often mRNA) or mRNA translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA.
3 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
3 O59924 (/IMP) O59924 (/IMP) O59924 (/IMP)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
3 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
3 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP)
Cellular response to sucrose stimulus GO:0071329
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
3 P24704 (/IEP) P24704 (/IEP) P24704 (/IEP)
Seed trichome elongation GO:0090378
The process in which a seed trichome irreversibly increases in size in one
3 B2LYR9 (/IEP) B2LYS0 (/IEP) D2D329 (/IEP)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
2 P93800 (/IEP) P93801 (/IEP)
Response to xenobiotic stimulus GO:0009410
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
2 O73872 (/IDA) O73872 (/IDA)
Response to xenobiotic stimulus GO:0009410
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
2 P93800 (/IEP) P93801 (/IEP)
Response to herbicide GO:0009635
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.
2 C1BFL3 (/IDA) Q8QHI0 (/IDA)
UV protection GO:0009650
Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.
2 A1Z8K9 (/IDA) Q7JR71 (/IDA)
Response to metal ion GO:0010038
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
2 O73872 (/IDA) O73872 (/IDA)
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
2 P00442 (/IDA) P07632 (/IDA)
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
2 P07632 (/TAS) P08228 (/TAS)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
2 P93800 (/TAS) P93801 (/TAS)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 P07632 (/IMP) P08228 (/IMP)
Hydrogen peroxide biosynthetic process GO:0050665
The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
2 P07632 (/IMP) P08228 (/IMP)
Response to methylmercury GO:0051597
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.
2 O73872 (/IDA) O73872 (/IDA)
Neuron cellular homeostasis GO:0070050
The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.
2 O73872 (/IMP) O73872 (/IMP)
Secondary cell wall biogenesis involved in seed trichome differentiation GO:0090379
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete.
2 B2LYR9 (/IEP) B2LYS0 (/IEP)
Activation of MAPK activity GO:0000187
The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
1 P08228 (/IDA)
Protein polyubiquitination GO:0000209
Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
1 P00442 (/ISS)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
1 P08228 (/IMP)
Response to superoxide GO:0000303
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
1 P08228 (/IMP)
Response to superoxide GO:0000303
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
1 P08228 (/ISO)
Ovarian follicle development GO:0001541
The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
1 P08228 (/IMP)
Regulation of cytokine production GO:0001817
Any process that modulates the frequency, rate, or extent of production of a cytokine.
1 P00442 (/IDA)
Positive regulation of cytokine production GO:0001819
Any process that activates or increases the frequency, rate or extent of production of a cytokine.
1 P08228 (/ISO)
Retina homeostasis GO:0001895
A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.
1 P08228 (/IMP)
Response to amphetamine GO:0001975
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
1 P07632 (/IEP)
Myeloid cell homeostasis GO:0002262
The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1 P08228 (/IGI)
Myeloid cell homeostasis GO:0002262
The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1 P08228 (/IMP)
Glutathione metabolic process GO:0006749
The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
1 P08228 (/IMP)
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
1 P08228 (/ISO)
Superoxide metabolic process GO:0006801
The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
1 P07632 (/TAS)
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
1 P28758 (/ISS)
Cellular iron ion homeostasis GO:0006879
Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
1 P08228 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P08228 (/IDA)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q55GQ5 (/IEP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P08228 (/ISO)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q54G70 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 P08228 (/IMP)
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
1 P08228 (/IMP)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
1 P08228 (/IMP)
Cell aging GO:0007569
An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).
1 P08228 (/ISO)
Sensory perception of sound GO:0007605
The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
1 P08228 (/IMP)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
1 P08228 (/IMP)
Anterograde axonal transport GO:0008089
The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.
1 P08228 (/IMP)
Retrograde axonal transport GO:0008090
The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.
1 P08228 (/IMP)
Regulation of blood pressure GO:0008217
Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
1 P08228 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 P08228 (/IMP)
Response to UV GO:0009411
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
1 Q54TU5 (/IMP)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 Q55GQ5 (/HEP)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
1 P08228 (/ISO)
Cellular response to iron ion starvation GO:0010106
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
1 Q9HEY7 (/IEP)
Transmission of nerve impulse GO:0019226
The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission.
1 P08228 (/IMP)
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
1 P08228 (/IGI)
Removal of superoxide radicals GO:0019430
Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
1 P08228 (/ISO)
Aggregation involved in sorocarp development GO:0031152
The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
1 Q55GQ5 (/IMP)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
1 P07632 (/IDA)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
1 P07632 (/IEP)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
1 P08228 (/ISO)
Peripheral nervous system myelin maintenance GO:0032287
The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.
1 P08228 (/IMP)
Positive regulation of superoxide anion generation GO:0032930
Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
1 P08228 (/ISO)
Response to carbon monoxide GO:0034465
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.
1 P07632 (/IEP)
Cellular response to potassium ion GO:0035865
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
1 P07632 (/IEP)
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
1 P08228 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P08228 (/IMP)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 Q55GQ5 (/IEP)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 P08228 (/IMP)
Superoxide anion generation GO:0042554
The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.
1 P08228 (/IDA)
Superoxide anion generation GO:0042554
The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.
1 Q54G70 (/ISS)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 P08228 (/IDA)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 P08228 (/ISO)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
1 P08228 (/ISO)
Regulation of GTPase activity GO:0043087
Any process that modulates the rate of GTP hydrolysis by a GTPase.
1 P08228 (/ISO)
Proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
1 P00442 (/ISS)
Negative regulation of neuron apoptotic process GO:0043524
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
1 P08228 (/IMP)
Interspecies interaction between organisms GO:0044419
Any process in which an organism has an effect on an organism of a different species.
1 P00442 (/IDA)
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
1 P28758 (/IMP)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
1 P08228 (/IMP)
Negative regulation of cholesterol biosynthetic process GO:0045541
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
1 P08228 (/ISO)
Regulation of protein kinase activity GO:0045859
Any process that modulates the frequency, rate or extent of protein kinase activity.
1 P08228 (/ISO)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
1 P07632 (/IEP)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 P07632 (/IMP)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 P08228 (/ISO)
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
1 P08228 (/IMP)
Response to axon injury GO:0048678
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
1 P08228 (/IMP)
Hydrogen peroxide biosynthetic process GO:0050665
The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
1 P08228 (/ISO)
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
1 P08228 (/IGI)
Positive regulation of phagocytosis GO:0050766
Any process that activates or increases the frequency, rate or extent of phagocytosis.
1 P08228 (/IGI)
Positive regulation of nitric-oxide synthase biosynthetic process GO:0051770
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.
1 P00442 (/IDA)
Regulation of mitochondrial membrane potential GO:0051881
Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
1 P00442 (/IDA)
Regulation of mitochondrial membrane potential GO:0051881
Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
1 P08228 (/ISO)
Heart contraction GO:0060047
The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
1 P08228 (/IMP)
Heart contraction GO:0060047
The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
1 P08228 (/ISO)
Neurofilament cytoskeleton organization GO:0060052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.
1 P08228 (/IGI)
Neurofilament cytoskeleton organization GO:0060052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.
1 P08228 (/IMP)
Relaxation of vascular smooth muscle GO:0060087
A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.
1 P08228 (/IMP)
Auditory receptor cell stereocilium organization GO:0060088
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
1 P08228 (/IMP)
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 P07632 (/IEP)
Cellular response to ATP GO:0071318
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
1 P07632 (/IEP)
Cellular response to high light intensity GO:0071486
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
1 Q9FK60 (/IEP)
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
1 P08228 (/ISO)
Response to antipsychotic drug GO:0097332
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
1 P07632 (/IEP)
Positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway GO:1902177
Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.
1 P08228 (/ISO)
Response to curcumin GO:1904643
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.
1 Q55GQ5 (/IDA)

There are 64 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
35 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P28758 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS)
(25 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
34 H6BDU4 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS)
(24 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
34 H6BDU4 (/ISS) P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS)
(24 more)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
34 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(24 more)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
33 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(23 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
32 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(22 more)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
32 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(22 more)
Dendrite cytoplasm GO:0032839
All of the contents of a dendrite, excluding the surrounding plasma membrane.
32 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(22 more)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
32 P00442 (/ISS) P04178 (/ISS) P04178 (/ISS) P07632 (/ISS) P08228 (/ISS) P09212 (/ISS) P33431 (/ISS) P60052 (/ISS) P60052 (/ISS) P60052 (/ISS)
(22 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
31 B2LYR9 (/IDA) B2LYS0 (/IDA) D2D329 (/IDA) H7BYH4 (/IDA) H7BYH4 (/IDA) O59924 (/IDA) O59924 (/IDA) O59924 (/IDA) P00441 (/IDA) P00441 (/IDA)
(21 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
20 B2LYR9 (/IDA) B2LYS0 (/IDA) D2D329 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00445 (/IDA) P00445 (/IDA)
(10 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
12 H7BYH4 (/IDA) H7BYH4 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) V9HWC9 (/IDA) V9HWC9 (/IDA) V9HWC9 (/IDA)
(2 more)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
12 O59924 (/IDA) O59924 (/IDA) O59924 (/IDA) P00445 (/IDA) P00445 (/IDA) P00445 (/IDA) P00445 (/IDA) P00445 (/IDA) P00445 (/IDA) P00445 (/IDA)
(2 more)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
12 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P07632 (/IDA) P61851 (/IDA) P61851 (/IDA) P61851 (/IDA) P61851 (/IDA)
(2 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
11 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P07632 (/IDA) P61851 (/IDA) P61851 (/IDA) P61851 (/IDA) P61851 (/IDA)
(1 more)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
10 A1Z8K9 (/IDA) C1BFL3 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P08228 (/IDA) Q7JR71 (/IDA) Q8QHI0 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
10 P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P00441 (/ISS) P61851 (/ISS) P61851 (/ISS) P61851 (/ISS) P61851 (/ISS) P61851 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
9 P00445 (/HDA) P00445 (/HDA) P00445 (/HDA) P00445 (/HDA) P00445 (/HDA) P00445 (/HDA) P00445 (/HDA) P00445 (/HDA) P08228 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P24704 (/TAS) P24704 (/TAS) P24704 (/TAS)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
7 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00442 (/IDA) P07632 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
7 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00442 (/IDA) P07632 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
6 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P07632 (/IDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
6 P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P08228 (/TAS)
Dendrite cytoplasm GO:0032839
All of the contents of a dendrite, excluding the surrounding plasma membrane.
6 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00442 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5 P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS) P00441 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 P00441 (/HDA) P00441 (/HDA) P00441 (/HDA) P00441 (/HDA) P00441 (/HDA)
Mitochondrial matrix GO:0005759
The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
5 P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS) P00441 (/NAS)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
5 P61851 (/ISM) P61851 (/ISM) P61851 (/ISM) P61851 (/ISM) P61851 (/ISM)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
5 P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA) P00441 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P00441 (/HDA) P00441 (/HDA) P00441 (/HDA) P00441 (/HDA) P00441 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 O59924 (/NAS) O59924 (/NAS) O59924 (/NAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 P07632 (/IDA) Q9HEY7 (/IDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
2 B2LYR9 (/IDA) B2LYS0 (/IDA)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
2 F1N8Q1 (/IDA) P80566 (/IDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
2 P08228 (/ISO) P28758 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 A1Z8K9 (/HDA) Q7JR71 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 P08228 (/ISO)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P08228 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P08228 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P08228 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P08228 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P08228 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P08228 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 P08228 (/ISO)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
1 Q54G70 (/ISS)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 P07632 (/IDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 P08228 (/ISO)
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
1 Q9FK60 (/IDA)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 P08228 (/ISO)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 Q9FK60 (/NAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P08228 (/ISO)
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
1 P07632 (/IDA)
Secretory granule GO:0030141
A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
1 P08228 (/ISO)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
1 Q55GQ5 (/HDA)
Dense core granule GO:0031045
Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.
1 P07632 (/IDA)
Dense core granule GO:0031045
Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.
1 P08228 (/ISO)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 P08228 (/ISO)
Dendrite cytoplasm GO:0032839
All of the contents of a dendrite, excluding the surrounding plasma membrane.
1 P08228 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 P08228 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 P07632 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 P08228 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 P08228 (/ISO)
Myelin sheath GO:0043209
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
1 P08228 (/HDA)
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
1 Q55GQ5 (/HDA)