View in Gene3D

CATH Superfamily 2.60.40.10

Immunoglobulins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 921: sialoadhesin isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 32 A7LCJ3 (/IPI) A7LCJ3 (/IPI) A7LCJ3 (/IPI) A7LCJ3 (/IPI) A7LCJ3 (/IPI) A7LCJ3 (/IPI) A7LCJ3 (/IPI) A7LCJ3 (/IPI) J9S2W1 (/IPI) J9S2W1 (/IPI)
(22 more)
Virion binding GO:0046790
Interacting selectively and non-covalently with a virion, either by binding to components of the capsid or the viral envelope.
 24 A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) J9S2W1 (/IDA) J9S2W1 (/IDA)
(14 more)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Viral entry into host cell GO:0046718
The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
 24 A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) J9S2W1 (/IMP) J9S2W1 (/IMP)
(14 more)
Negative regulation of phagocytosis GO:0050765
Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.
 24 A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) J9S2W1 (/IMP) J9S2W1 (/IMP)
(14 more)
Clathrin-dependent endocytosis GO:0072583
An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
 24 A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) J9S2W1 (/IMP) J9S2W1 (/IMP)
(14 more)
Clathrin-dependent endocytosis of virus by host cell GO:0075512
Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.
 24 A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) A7LCJ3 (/IMP) J9S2W1 (/IMP) J9S2W1 (/IMP)
(14 more)
Positive regulation of T cell apoptotic process GO:0070234
Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.
 8 Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP)
Positive regulation of extrinsic apoptotic signaling pathway GO:2001238
Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.
 8 Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP) Q62230 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
 24 A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) J9S2W1 (/IDA) J9S2W1 (/IDA)
(14 more)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
 24 A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) J9S2W1 (/IDA) J9S2W1 (/IDA)
(14 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 24 A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) J9S2W1 (/IDA) J9S2W1 (/IDA)
(14 more)
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
 24 A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) A7LCJ3 (/IDA) J9S2W1 (/IDA) J9S2W1 (/IDA)
(14 more)