The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Immunoglobulins
".
FunFam 844: roundabout homolog 4 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q8C310 (/IPI) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
1 | Q8C310 (/IDA) |
|
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
|
1 | Q8WZ75 (/TAS) |
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
1 | Q8WZ75 (/IGI) |
|
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
1 | A0A2R8QSX8 (/IMP) |
|
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
1 | Q8C310 (/ISO) |
|
Positive regulation of cell-matrix adhesion GO:0001954
Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
|
1 | A0A2R8QSX8 (/IDA) |
|
Lamellipodium assembly GO:0030032
Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
1 | A0A2R8QSX8 (/IDA) |
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
1 | A0A2R8QSX8 (/IMP) |
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
1 | Q8WZ75 (/NAS) |
|
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
1 | Q8C310 (/IDA) |
|
Positive regulation of Rac protein signal transduction GO:0035022
Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.
|
1 | A0A2R8QSX8 (/IDA) |
|
Positive regulation of Rac protein signal transduction GO:0035022
Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.
|
1 | A0A2R8QSX8 (/IMP) |
|
Endothelial cell migration GO:0043542
The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | A0A2R8QSX8 (/IDA) |
|
Filopodium assembly GO:0046847
The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
|
1 | A0A2R8QSX8 (/IDA) |
|
Positive regulation of small GTPase mediated signal transduction GO:0051057
Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.
|
1 | A0A2R8QSX8 (/IDA) |
|
Positive regulation of small GTPase mediated signal transduction GO:0051057
Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.
|
1 | A0A2R8QSX8 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q8C310 (/TAS) Q8WZ75 (/TAS) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
1 | Q8C310 (/IDA) |
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | A0A2R8QSX8 (/ISS) |
|
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
1 | A0A2R8QSX8 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | Q8WZ75 (/HDA) |