The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Immunoglobulins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 34: Titin isoform A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Structural constituent of muscle GO:0008307
The action of a molecule that contributes to the structural integrity of a muscle fiber.
73 A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP)
(63 more)
Structural constituent of muscle GO:0008307
The action of a molecule that contributes to the structural integrity of a muscle fiber.
1 O76281 (/IDA)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
173 A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI)
(163 more)
Myofibril assembly GO:0030239
Formation of myofibrils, the repeating units of striated muscle.
173 A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI)
(163 more)
Sarcomerogenesis GO:0048769
The process in which sarcomeres are added in series within a fiber.
173 A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI)
(163 more)
Sarcomerogenesis GO:0048769
The process in which sarcomeres are added in series within a fiber.
173 A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP)
(163 more)
Striated muscle myosin thick filament assembly GO:0071688
The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle.
173 A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI) A0A2R8PZT6 (/IGI)
(163 more)
Skeletal myofibril assembly GO:0014866
The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.
100 A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP) A0A2R8PZT6 (/IMP)
(90 more)
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
74 A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP)
(64 more)
Cell morphogenesis GO:0000902
The developmental process in which the size or shape of a cell is generated and organized.
73 A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP)
(63 more)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
73 A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP)
(63 more)
Skeletal muscle tissue development GO:0007519
The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
73 A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP)
(63 more)
Cardiac muscle tissue development GO:0048738
The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.
73 A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP)
(63 more)
Heart contraction GO:0060047
The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
73 A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP) A5X6X5 (/IMP)
(63 more)
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
1 O76281 (/IEP)
Muscle thin filament assembly GO:0071689
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.
1 O76281 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Sarcomere GO:0030017
The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
1 O76281 (/IDA)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
1 O76281 (/IDA)
I band GO:0031674
A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.
1 O76281 (/IDA)