The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Substrate Binding Domain Of DNAk; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 3: Molecular chaperone DnaK

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Fibronectin binding GO:0001968
Interacting selectively and non-covalently with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
11 P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI)
(1 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
11 A0A0H3L5C8 (/IPI) A0A0H3L5C8 (/IPI) A0A0H3L5C8 (/IPI) A0A0H3L5C8 (/IPI) A0A0H3L5C8 (/IPI) A0A0H3L5C8 (/IPI) A0A0H3L5C8 (/IPI) A0A0H3L5C8 (/IPI) A0A0H3L5C8 (/IPI) A0A0H3L5C8 (/IPI)
(1 more)
Zymogen binding GO:0035375
Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.
11 P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI) P9WMJ9 (/IPI)
(1 more)
Host cell surface binding GO:0046812
Interacting selectively and non-covalently with the surface of a host cell.
11 A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA)
(1 more)
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
5 B7GT47 (/IPI) B7GT47 (/IPI) B7GT47 (/IPI) Q1G1L9 (/IPI) Q1G1M0 (/IPI)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
11 P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP)
(1 more)
Positive regulation of plasminogen activation GO:0010756
Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
11 P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA)
(1 more)
Interaction with host via substance in symbiont surface GO:0044044
An interaction with the host organism mediated by a substance on the surface of the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
11 P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA)
(1 more)
Response to antibiotic GO:0046677
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
11 P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP)
(1 more)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
11 P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP)
(1 more)
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
11 P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA)
(1 more)
Cellular response to superoxide GO:0071451
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
11 P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP) P9WMJ9 (/IEP)
(1 more)
Positive regulation of transcription regulatory region DNA binding GO:2000679
Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.
11 P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA)
(1 more)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Bacterial extracellular vesicle GO:0097691
Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells.
22 A1KFH2 (/IDA) A1KFH2 (/IDA) A1KFH2 (/IDA) A1KFH2 (/IDA) A1KFH2 (/IDA) A1KFH2 (/IDA) A1KFH2 (/IDA) A1KFH2 (/IDA) A1KFH2 (/IDA) A1KFH2 (/IDA)
(12 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
16 B7GT47 (/IDA) B7GT47 (/IDA) B7GT47 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA)
(6 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
11 P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA)
(1 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
11 P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA)
(1 more)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
11 P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
11 P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA)
(1 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA) P9WMJ9 (/HDA)
(1 more)
Capsule GO:0042603
A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication.
11 P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA) P9WMJ9 (/IDA)
(1 more)
Host cell surface GO:0044228
The external part of the host cell wall and/or host plasma membrane.
11 A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA) A0A0H3L5C8 (/IDA)
(1 more)