The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
978
3D
2e63A00 - 94.3
2
836
3D
5c33B00 - 87.0
3
763
3D
5vsnA00 - 93.0
4
646
3D
2iwgE00 - 93.5
5
553
3D
4kg0A01 - 92.4
6
482 - - 93.6
7
368 - - 74.7
8
280
3D
5f6lB00 - 84.6
9
268 - - 75.9
11
263
3D
5jiuB00 - 72.4
10
256 - - 54.2
12
Cardiac
230 - - 69.5
13
216
3D
4xw3B00 - 78.7
14
211 - - 74.7
15
209
3D
4qt6A00 - 82.0
16
200 - - 72.9
17
193 - - 71.7
18
192 - - 72.5
20
168 - - 82.5
19
skeletal
168 - - 87.7
21
167 - - 79.5
22
159 - - 84.1
23
Predicted
150
3D
4b3nB02 - 84.5
24
140 - - 49.8
25
135 - - 82.3
26
124 - - 21.9
27
122
3D
3kb5A00 - 87.6
28
119 - - 35.9
29
114 - - 38.3
30
106 - - 28.6
31
106 - - 62.3
32
86 - - 39.5
33
78 - - 72.9
34
76 - - 40.3
35
75 - - 78.2
36
68 - - 43.8
40
68
3D
2fbeD00 - 95.5
37
67 - - 96.9
38
66 - - 47.1
39
65 - - 38.9
41
61 - - 15.3
45
61
3D
6flmC00 - 82.0
42
60 - - 62.5
43
58 - - 92.2
44
57 - - 88.8
46
55 - - 44.8
48
50 - - 85.4
47
50 - - 41.6
49
37 - - 12.4
51
35 - - 45.5
50
35 - - 78.4
52
33 - - 31.5
53
31 - - 74.0
54
Bre2
31 - - 73.1
55
29 - - 79.8
56
28 - - 36.7
60
24 - - 46.4
58
24 - - 62.0
57
24 - - 40.3
59
24 - - 81.9
61
23 - - 64.6
62
22 - - 32.5
63
21 - - 19.4
65
19 - - 66.0
64
19 - - 50.8
66
18 - - 80.4
67
17 - - 8.0
68
17 - - 4.5
69
16 - - 41.2
71
16 - - 86.2
72
16 - - 66.1
70
16 - - 72.5
76
15 - - 84.9
74
15 - - 78.1
75
15 - - 42.7
73
15 - - 85.1
77
14 - - 20.7
78
13 - - 70.6
80
12 - - 83.7
79
12 - - 79.7
82
11 - - 85.8
81
11 - - 9.5
84
Ubiquitin-transferase
10 - - 14.3
85
10 - - 0.8
83
Ubiquitin-transferase
10 - - 42.4
86
9 - - 78.7
87
8 - - 53.4
89
7 - - 84.2
90
7 - - 50.4
88
7 - - 8.3
92
6 - - 49.3
91
6 - - 9.8
94
5 - - 11.3
93
5 - - 21.1
99
4 - - 3.3
103
4 - - 64.6
96
4 - - 37.9
98
Ubiquitin-transferase
4 - - 5.3
102
4 - - 72.5
100
4 - - 0.0
101
4 - - 0.8
95
4 - - 19.7
104
4 - - 36.0
97
4 - - 12.5
112
3 - - 1.1
105
3 - - 12.2
110
3 - - 66.2
109
3 - - 0.0
107
3 - - 26.9
115
3 - - 24.3
111
3 - - 0.0
113
3 - - 68.3
116
3 - - 43.4
108
3 - - 35.0
106
3 - - 7.2
114
3 - - 29.3
129
2 - - 38.0
124
2 - - 1.4
131
2 - - 0.0
141
2 - - 0.0
119
2 - - 11.3
126
2 - - 0.0
143
2 - - 42.6
133
2 - - 7.0
137
2 - - 0.0
147
2 - - 26.7
117
2 - - 47.1
135
2 - - 0.0
145
2 - - 37.5
121
2 - - 0.0
130
2 - - 47.8
140
2 - - 31.6
123
2 - - 11.3
142
2 - - 6.1
128
2 - - 0.0
132
2 - - 0.0
139
2 - - 0.6
144
2 - - 16.0
125
Ubiquitin-transferase
2 - - 0.0
118
2 - - 42.9
134
2 - - 0.0
127
3 copies
2 - - 0.0
136
2 - - 4.4
120
2 - - 0.0
146
2 - - 39.8
138
2 - - 0.0
122
2 - - 2.4
170
1 - - 0.0
207
1 - - 0.0
184
1 - - 0.0
181
1 - - 0.0
165
1 - - 0.0
168
1 - - 0.0
192
1 - - 0.0
199
1 - - 0.0
148
1 - - 0.0
157
1 - - 0.0
179
1 - - 0.0
193
1 - - 0.0
205
1 - - 0.0
163
1 - - 0.0
186
1 - - 0.0
176
1 - - 0.0
215
1 - - 0.0
180
1 - - 0.0
187
1 - - 0.0
212
1 - - 0.0
175
1 - - 0.0
202
1 - - 0.0
154
1 - - 0.0
152
1 - - 0.0
200
1 - - 0.0
211
1 - - 0.0
160
1 - - 0.0
189
1 - - 0.0
182
1 - - 0.0
167
1 - - 0.0
206
1 - - 0.0
197
1 - - 0.0
150
1 - - 0.0
159
1 - - 0.0
162
1 - - 0.0
169
1 - - 0.0
190
1 - - 0.0
172
1 - - 0.0
191
1 - - 0.0
158
1 - - 0.0
209
1 - - 0.0
149
1 - - 0.0
178
1 - - 0.0
183
1 - - 0.0
204
1 - - 0.0
177
1 - - 0.0
214
1 - - 0.0
156
1 - - 0.0
196
1 - - 0.0
194
1 - - 0.0
171
1 - - 0.0
166
NMD candidate
1 - - 0.0
185
1 - - 0.0
153
1 - - 0.0
155
1 - - 0.0
198
1 - - 0.0
210
1 - - 0.0
213
1 - - 0.0
161
1 - - 0.0
195
1 - - 0.0
174
1 - - 0.0
188
1 - - 0.0
203
1 - - 0.0
164
1 - - 0.0
151
1 - - 0.0
173
1 - - 0.0
208
1 - - 0.0
201
1 - - 0.0