The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: Protein eva-1 homolog C

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Galactose binding GO:0005534
Interacting selectively and non-covalently with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.
16 A2TJV1 (/ISS) A2TJV1 (/ISS) B5X714 (/ISS) B5X714 (/ISS) P86177 (/ISS) P86177 (/ISS) P86178 (/ISS) P86178 (/ISS) P86179 (/ISS) P86179 (/ISS)
(6 more)
Rhamnose binding GO:0033296
Interacting selectively and non-covalently with the D- or L-enantiomer of rhamnose.
16 A2TJV1 (/ISS) A2TJV1 (/ISS) B5X714 (/ISS) B5X714 (/ISS) P86177 (/ISS) P86177 (/ISS) P86178 (/ISS) P86178 (/ISS) P86179 (/ISS) P86179 (/ISS)
(6 more)
Melibiose binding GO:1903777
Interacting selectively and non-covalently with melibiose.
16 A2TJV1 (/ISS) A2TJV1 (/ISS) B5X714 (/ISS) B5X714 (/ISS) P86177 (/ISS) P86177 (/ISS) P86178 (/ISS) P86178 (/ISS) P86179 (/ISS) P86179 (/ISS)
(6 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
12 A2TJV1 (/ISS) A2TJV1 (/ISS) B5X714 (/ISS) B5X714 (/ISS) P86178 (/ISS) P86178 (/ISS) P86179 (/ISS) P86179 (/ISS) Q7LZR7 (/ISS) Q7LZR7 (/ISS)
(2 more)
Galactose binding GO:0005534
Interacting selectively and non-covalently with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.
8 A0A060XUW4 (/IDA) A0A060XUW4 (/IDA) Q9IB51 (/IDA) Q9IB51 (/IDA) Q9IB52 (/IDA) Q9IB52 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Rhamnose binding GO:0033296
Interacting selectively and non-covalently with the D- or L-enantiomer of rhamnose.
8 A0A060XUW4 (/IDA) A0A060XUW4 (/IDA) Q9IB51 (/IDA) Q9IB51 (/IDA) Q9IB52 (/IDA) Q9IB52 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Melibiose binding GO:1903777
Interacting selectively and non-covalently with melibiose.
8 A0A060XUW4 (/IDA) A0A060XUW4 (/IDA) Q9IB51 (/IDA) Q9IB51 (/IDA) Q9IB52 (/IDA) Q9IB52 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 Q9IB52 (/IPI) Q9IB52 (/IPI) Q9IB53 (/IPI) Q9IB53 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
4 Q9IB51 (/IDA) Q9IB51 (/IDA) Q9IB52 (/IDA) Q9IB52 (/IDA)
RBL family protein binding GO:0061675
Interacting selectively and non-covalently with any member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose.
4 Q9IB51 (/IDA) Q9IB51 (/IDA) Q9IB52 (/IDA) Q9IB52 (/IDA)
Phosphoprotein binding GO:0051219
Interacting selectively and non-covalently with a phosphorylated protein.
2 Q9IB52 (/IPI) Q9IB52 (/IPI)
Importin-alpha family protein binding GO:0061676
Interacting selectively and non-covalently with any member of the importin-alpha family.
2 Q9IB51 (/IMP) Q9IB51 (/IMP)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
1 P58658 (/IMP)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
1 P58659 (/ISO)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Erythrocyte aggregation GO:0034117
The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules.
4 Q9IB52 (/IMP) Q9IB52 (/IMP) Q9IB53 (/IMP) Q9IB53 (/IMP)
Protein trimerization GO:0070206
The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.
4 Q9IB52 (/IDA) Q9IB52 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
3 A0A2R8QHE6 (/IGI) E9QFV1 (/IGI) F1QW66 (/IGI)
Response to virus GO:0009615
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
3 A0A2R8QHE6 (/IMP) E9QFV1 (/IMP) F1QW66 (/IMP)
NIK/NF-kappaB signaling GO:0038061
The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52).
3 A0A2R8QHE6 (/IGI) E9QFV1 (/IGI) F1QW66 (/IGI)
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
3 A0A2R8QHE6 (/IMP) E9QFV1 (/IMP) F1QW66 (/IMP)

There are 21 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
16 A2TJV1 (/ISS) A2TJV1 (/ISS) B5X714 (/ISS) B5X714 (/ISS) P86177 (/ISS) P86177 (/ISS) P86178 (/ISS) P86178 (/ISS) P86179 (/ISS) P86179 (/ISS)
(6 more)
Cortical granule GO:0060473
A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.
16 A2TJV1 (/ISS) A2TJV1 (/ISS) B5X714 (/ISS) B5X714 (/ISS) P86177 (/ISS) P86177 (/ISS) P86178 (/ISS) P86178 (/ISS) P86179 (/ISS) P86179 (/ISS)
(6 more)
Female germ cell nucleus GO:0001674
The nucleus of the female germ cell, a reproductive cell in females.
8 A2TJV1 (/ISS) A2TJV1 (/ISS) P86179 (/ISS) P86179 (/ISS) Q7LZR7 (/ISS) Q7LZR7 (/ISS) Q8UW56 (/ISS) Q8UW56 (/ISS)
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
8 A0A060XUW4 (/IDA) A0A060XUW4 (/IDA) Q9IB51 (/IDA) Q9IB51 (/IDA) Q9IB52 (/IDA) Q9IB52 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 A2TJV1 (/ISS) A2TJV1 (/ISS) P86179 (/ISS) P86179 (/ISS) Q7LZR7 (/ISS) Q7LZR7 (/ISS) Q8UW56 (/ISS) Q8UW56 (/ISS)
NLS-dependent protein nuclear import complex GO:0042564
A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore.
8 A2TJV1 (/ISS) A2TJV1 (/ISS) P86179 (/ISS) P86179 (/ISS) Q7LZR7 (/ISS) Q7LZR7 (/ISS) Q8UW56 (/ISS) Q8UW56 (/ISS)
Cortical granule GO:0060473
A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.
8 A0A060XUW4 (/IDA) A0A060XUW4 (/IDA) Q9IB51 (/IDA) Q9IB51 (/IDA) Q9IB52 (/IDA) Q9IB52 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 A0A060XUW4 (/IDA) A0A060XUW4 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 P86177 (/ISS) P86177 (/ISS) Q8UW57 (/ISS) Q8UW57 (/ISS)
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
4 A0A060XUW4 (/IDA) A0A060XUW4 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Cytoplasmic side of plasma membrane GO:0009898
The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
4 P86177 (/ISS) P86177 (/ISS) Q8UW57 (/ISS) Q8UW57 (/ISS)
Germinal vesicle GO:0042585
The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.
4 A0A060XUW4 (/IDA) A0A060XUW4 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Germinal vesicle GO:0042585
The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.
4 P86177 (/ISS) P86177 (/ISS) Q8UW57 (/ISS) Q8UW57 (/ISS)
Perivitelline space GO:0098595
The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane).
4 A0A060XUW4 (/IDA) A0A060XUW4 (/IDA) Q9IB53 (/IDA) Q9IB53 (/IDA)
Perivitelline space GO:0098595
The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane).
4 P86177 (/ISS) P86177 (/ISS) Q8UW57 (/ISS) Q8UW57 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 A0A2R8QHE6 (/IMP) E9QFV1 (/IMP) F1QW66 (/IMP)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 A0A2R8QHE6 (/IMP) E9QFV1 (/IMP) F1QW66 (/IMP)
Female germ cell nucleus GO:0001674
The nucleus of the female germ cell, a reproductive cell in females.
2 Q9IB51 (/IDA) Q9IB51 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9IB51 (/IDA) Q9IB51 (/IDA)
Nematocyst GO:0042151
An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus.
2 E0D8Q3 (/IDA) E0D8Q4 (/IDA)
NLS-dependent protein nuclear import complex GO:0042564
A dimer consisting of an alpha and a beta-subunit that imports proteins with an NLS into the nucleus through a nuclear pore.
2 Q9IB51 (/IDA) Q9IB51 (/IDA)