The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleoplasmin core domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: nucleoplasmin-like protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
8 Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
5 Q27415 (/TAS) Q27415 (/TAS) Q27415 (/TAS) Q27415 (/TAS) Q27415 (/TAS)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
8 Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA)
Sperm chromatin decondensation GO:0035041
Unwinding of the condensed nuclear chromatin of an inactive sperm nucleus.
8 Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA) Q9VAC4 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 Q27415 (/HDA) Q27415 (/HDA) Q27415 (/HDA) Q27415 (/HDA) Q27415 (/HDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
5 Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA) Q27415 (/IDA)