The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: DNA-directed RNA polymerase subunit beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-directed 5'-3' RNA polymerase activity GO:0003899
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1 Q10233 (/NAS)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of type I interferon production GO:0032481
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
14 Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS)
(4 more)
Positive regulation of interferon-beta production GO:0032728
Any process that activates or increases the frequency, rate, or extent of interferon-beta production.
14 Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP)
(4 more)
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
14 Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP) Q9NW08 (/IMP)
(4 more)
Termination of RNA polymerase III transcription GO:0006386
The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues.
6 P22276 (/TAS) P22276 (/TAS) P22276 (/TAS) P22276 (/TAS) P22276 (/TAS) P22276 (/TAS)
TRNA transcription by RNA polymerase III GO:0042797
The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.
6 P22276 (/IDA) P22276 (/IDA) P22276 (/IDA) P22276 (/IDA) P22276 (/IDA) P22276 (/IDA)
TRNA transcription by RNA polymerase III GO:0042797
The synthesis of transfer RNA (tRNA) from a DNA template by RNA polymerase III (Pol III), originating at a Pol III promoter.
6 P22276 (/IGI) P22276 (/IGI) P22276 (/IGI) P22276 (/IGI) P22276 (/IGI) P22276 (/IGI)
Megagametogenesis GO:0009561
The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center.
2 F4KD38 (/IMP) F4KD38 (/IMP)
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
1 Q10233 (/NAS)
TRNA transcription GO:0009304
The synthesis of transfer RNA (tRNA) from a DNA template.
1 F1QQA2 (/IMP)
Exocrine pancreas development GO:0031017
The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
1 F1QQA2 (/IMP)
Positive regulation of interferon-beta production GO:0032728
Any process that activates or increases the frequency, rate, or extent of interferon-beta production.
1 P59470 (/ISO)
Positive regulation of interferon-beta production GO:0032728
Any process that activates or increases the frequency, rate, or extent of interferon-beta production.
1 P59470 (/ISS)
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 P59470 (/ISO)
Positive regulation of innate immune response GO:0045089
Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 P59470 (/ISS)
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
1 F1QQA2 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
20 P22276 (/TAS) P22276 (/TAS) P22276 (/TAS) P22276 (/TAS) P22276 (/TAS) P22276 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS)
(10 more)
RNA polymerase III complex GO:0005666
RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
20 P22276 (/IDA) P22276 (/IDA) P22276 (/IDA) P22276 (/IDA) P22276 (/IDA) P22276 (/IDA) Q9NW08 (/IDA) Q9NW08 (/IDA) Q9NW08 (/IDA) Q9NW08 (/IDA)
(10 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
14 Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS) Q9NW08 (/TAS)
(4 more)
RNA polymerase III complex GO:0005666
RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
1 P59470 (/ISO)
RNA polymerase III complex GO:0005666
RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
1 Q10233 (/NAS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q10233 (/HDA)