The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: DNA-directed RNA polymerase subunit beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
12 Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS)
(2 more)
DNA-directed 5'-3' RNA polymerase activity GO:0003899
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
12 Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS)
(2 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription by RNA polymerase I GO:0006360
The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.
12 Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS)
(2 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA polymerase I complex GO:0005736
RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
12 Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS) Q8II17 (/ISS)
(2 more)