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CATH Superfamily 2.40.50.140

Nucleic acid-binding proteins

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 47: tyrosine--tRNA ligase, cytoplasmic isoform X2

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Tyrosine--tRNA ligase. [EC: 6.1.1.1]
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).
    		 15 A0A0S2Z4R1 A0A0S2Z4R1 A8KBY3 A8KBY3 P54577 P54577 Q29465 Q4KM49 Q5R8T5 Q5ZJ08
    (5 more...)
    Methionine--tRNA ligase. [EC: 6.1.1.10]
    ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).
    • In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.
    		 6 B9FTH9 B9FTH9 Q20970 Q9SVN5 Q9ZTS1 Q9ZTS1