The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 40: Ribonuclease E

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
9 P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
9 P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI)
7S RNA binding GO:0008312
Interacting selectively and non-covalently with 7S RNA, the RNA component of the signal recognition particle (SRP).
9 P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP)
Ribonuclease E activity GO:0008995
Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
9 P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA)
DEAD/H-box RNA helicase binding GO:0017151
Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase.
9 P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
9 P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI)
Ribonuclease E activity GO:0008995
Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
7 Q608K9 (/ISS) Q8EDG6 (/ISS) Q9KQG8 (/ISS) Q9KQG8 (/ISS) Q9KQG8 (/ISS) Q9KQG8 (/ISS) Q9KQG8 (/ISS)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RRNA 5'-end processing GO:0000967
Any process involved in forming the mature 5' end of an rRNA molecule.
9 P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP)
RNA catabolic process GO:0006401
The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
9 P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA) P21513 (/IDA)
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
9 P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP)
TRNA processing GO:0008033
The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
9 P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
9 P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI) P21513 (/IPI)
Regulation of RNA helicase activity GO:1902280
Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity.
9 P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP) P21513 (/IMP)
RNA processing GO:0006396
Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
6 Q8EDG6 (/ISS) Q9KQG8 (/ISS) Q9KQG8 (/ISS) Q9KQG8 (/ISS) Q9KQG8 (/ISS) Q9KQG8 (/ISS)
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
1 Q608K9 (/ISS)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.