The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nucleic acid-binding proteins
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: 30S ribosomal protein S12

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
736 C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA)
(726 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
557 P0A0X4 (/IPI) P0A0X4 (/IPI) P0A0X4 (/IPI) P0A0X4 (/IPI) P0A0X4 (/IPI) P0A0X4 (/IPI) P0A0X4 (/IPI) P0A0X4 (/IPI) P0A0X4 (/IPI) P0A0X4 (/IPI)
(547 more)
RRNA binding GO:0019843
Interacting selectively and non-covalently with ribosomal RNA.
368 P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA)
(358 more)
Misfolded RNA binding GO:0034336
Interacting selectively and non-covalently with an RNA molecule that has assumed an incorrect conformation.
368 P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA)
(358 more)
Structural constituent of ribosome GO:0003735
The action of a molecule that contributes to the structural integrity of the ribosome.
11 Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS)
(1 more)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal small subunit assembly GO:0000028
The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
368 C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA)
(358 more)
Group I intron splicing GO:0000372
The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).
368 P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA)
(358 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
368 P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP)
(358 more)
Positive regulation of RNA splicing GO:0033120
Any process that activates or increases the frequency, rate or extent of RNA splicing.
368 P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA)
(358 more)
RNA folding GO:0034337
The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.
368 P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA)
(358 more)
Maintenance of translational fidelity GO:1990145
Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template.
368 P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP) P0A7S3 (/IMP)
(358 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
11 Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS)
(1 more)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosolic small ribosomal subunit GO:0022627
The small subunit of a ribosome located in the cytosol.
736 C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA) C3SQR7 (/IDA)
(726 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
368 P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA) P0A7S3 (/IDA)
(358 more)
Cytosolic small ribosomal subunit GO:0022627
The small subunit of a ribosome located in the cytosol.
11 Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS) Q9KUZ9 (/ISS)
(1 more)