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CATH Superfamily 2.40.50.100

RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: DNA-directed RNA polymerase subunit beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 142 P0A8V2 (/IPI) P0A8V2 (/IPI) P0A8V2 (/IPI) P0A8V2 (/IPI) P0A8V2 (/IPI) P0A8V2 (/IPI) P0A8V2 (/IPI) P0A8V2 (/IPI) P0A8V2 (/IPI) P0A8V2 (/IPI)
(132 more)
DNA-directed 5'-3' RNA polymerase activity GO:0003899
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
 4 Q9KV30 (/ISS) Q9KV30 (/ISS) Q9KV30 (/ISS) Q9KV30 (/ISS)
DNA-directed 5'-3' RNA polymerase activity GO:0003899
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
 3 P50546 (/TAS) P50546 (/TAS) P50546 (/TAS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
 4 Q9KV30 (/ISS) Q9KV30 (/ISS) Q9KV30 (/ISS) Q9KV30 (/ISS)
DNA-templated transcription, elongation GO:0006354
The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
 3 P50546 (/TAS) P50546 (/TAS) P50546 (/TAS)
Cellular response to iron ion GO:0071281
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
 1 Q5F5R5 (/EXP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
 139 P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA)
(129 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
 139 P0A8V2 (/IDA) P0A8V2 (/IDA) P0A8V2 (/IDA) P0A8V2 (/IDA) P0A8V2 (/IDA) P0A8V2 (/IDA) P0A8V2 (/IDA) P0A8V2 (/IDA) P0A8V2 (/IDA) P0A8V2 (/IDA)
(129 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
 139 P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA) P0A8V2 (/HDA)
(129 more)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
 3 P50546 (/IDA) P50546 (/IDA) P50546 (/IDA)
Chloroplast nucleoid GO:0042644
The region of a chloroplast to which the DNA is confined.
 3 P50546 (/IDA) P50546 (/IDA) P50546 (/IDA)