The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Lyase, Ornithine Decarboxylase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: antizyme inhibitor 2 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q8BVM4 (/IPI) Q8BVM4 (/IPI) Q96A70 (/IPI)
Ornithine decarboxylase activator activity GO:0042978
Upregulation of the activity of the enzyme ornithine decarboxylase.
3 Q8BVM4 (/IDA) Q8BVM4 (/IDA) Q96A70 (/IDA)
Putrescine transmembrane transporter activity GO:0015489
Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
2 Q8BVM4 (/IDA) Q8BVM4 (/IDA)
Putrescine transmembrane transporter activity GO:0015489
Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
2 D4A693 (/ISS) Q96A70 (/ISS)
Ornithine decarboxylase activator activity GO:0042978
Upregulation of the activity of the enzyme ornithine decarboxylase.
2 Q8BVM4 (/IGI) Q8BVM4 (/IGI)
Ornithine decarboxylase activator activity GO:0042978
Upregulation of the activity of the enzyme ornithine decarboxylase.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Ornithine decarboxylase activator activity GO:0042978
Upregulation of the activity of the enzyme ornithine decarboxylase.
2 D4A693 (/ISS) Q96A70 (/ISS)
Arginine decarboxylase activity GO:0008792
Catalysis of the reaction: L-arginine + H(+) = agmatine + CO(2).
1 Q96A70 (/TAS)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of protein catabolic process GO:0042177
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
3 Q8BVM4 (/IDA) Q8BVM4 (/IDA) Q96A70 (/IDA)
Trans-Golgi network membrane organization GO:0098629
A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane.
3 D4A693 (/ISS) Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Ornithine metabolic process GO:0006591
The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
2 Q8BVM4 (/IDA) Q8BVM4 (/IDA)
Putrescine transport GO:0015847
The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
2 Q8BVM4 (/IDA) Q8BVM4 (/IDA)
Putrescine transport GO:0015847
The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
2 D4A693 (/ISS) Q96A70 (/ISS)
Negative regulation of protein catabolic process GO:0042177
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Negative regulation of protein catabolic process GO:0042177
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
2 D4A693 (/ISS) Q96A70 (/ISS)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
2 Q8BVM4 (/IDA) Q8BVM4 (/IDA)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
2 D4A693 (/ISS) Q96A70 (/ISS)
Trans-Golgi network membrane organization GO:0098629
A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Positive regulation of polyamine transmembrane transport GO:1902269
Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.
2 Q8BVM4 (/IDA) Q8BVM4 (/IDA)
Positive regulation of polyamine transmembrane transport GO:1902269
Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.
2 D4A693 (/ISS) Q96A70 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q96A70 (/NAS)
Agmatine biosynthetic process GO:0097055
The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase.
1 Q96A70 (/TAS)
Trans-Golgi network membrane organization GO:0098629
A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane.
1 Q96A70 (/IMP)

There are 33 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
3 D4A693 (/ISS) Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Transport vesicle GO:0030133
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
3 D4A693 (/ISS) Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
3 D4A693 (/ISS) Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
3 D4A693 (/ISS) Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
3 D4A693 (/ISS) Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
3 D4A693 (/ISS) Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 D4A693 (/ISS) Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 D4A693 (/IDA) Q96A70 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q8BVM4 (/IDA) Q8BVM4 (/IDA)
Cis-Golgi network GO:0005801
The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
2 Q8BVM4 (/IDA) Q8BVM4 (/IDA)
Cis-Golgi network GO:0005801
The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
2 D4A693 (/ISS) Q96A70 (/ISS)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Transport vesicle GO:0030133
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Endoplasmic reticulum-Golgi intermediate compartment membrane GO:0033116
The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.
2 Q8BVM4 (/IDA) Q8BVM4 (/IDA)
Endoplasmic reticulum-Golgi intermediate compartment membrane GO:0033116
The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.
2 D4A693 (/ISS) Q96A70 (/ISS)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Granular vesicle GO:1990005
A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells.
2 D4A693 (/IDA) Q96A70 (/IDA)
Granular vesicle GO:1990005
A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells.
2 Q8BVM4 (/ISO) Q8BVM4 (/ISO)
Granular vesicle GO:1990005
A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells.
2 Q8BVM4 (/ISS) Q8BVM4 (/ISS)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
1 Q96A70 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q96A70 (/TAS)
Transport vesicle GO:0030133
Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
1 Q96A70 (/IMP)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
1 Q96A70 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
1 Q96A70 (/IDA)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 Q96A70 (/IDA)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
1 Q96A70 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q96A70 (/IDA)