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CATH Superfamily 2.40.37.10

Lyase, Ornithine Decarboxylase; Chain A, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Lyase, Ornithine Decarboxylase; Chain A, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily EC Annotations

Note: the EC figure is not being displayed for this superfamily as there are more than 100 different EC terms.

There are 10 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Alanine racemase. [EC: 5.1.1.1]
L-alanine = D-alanine.
    		 795 A0A024L3P9 A0A026V3Z1 A0A059I382 A0A062X2Q2 A0A069B981 A0A069XPR2 A0A070FJ51 A0A070SNA0 A0A073FL04 A0A073GT42
    (785 more...)
    Arginine decarboxylase. [EC: 4.1.1.19]
    L-arginine = agmatine + CO(2).
      		 425 A0A015S533 A0A015TV55 A0A015U7D5 A0A015VJA0 A0A015X8T8 A0A015XMZ4 A0A016BSC1 A0A016C0V8 A0A016CLA0 A0A016CVF1
      (415 more...)
      Diaminopimelate decarboxylase. [EC: 4.1.1.20]
      Meso-2,6-diaminoheptanedioate = L-lysine + CO(2).
        		 148 A0A026V906 A0A037YCT9 A0A045JXB0 A0A070T4H2 A0A070UP03 A0A074HR49 A0A075WCH1 A0A080FM23 A0A085SUQ9 A0A0A8F9E4
        (138 more...)
        Ornithine decarboxylase. [EC: 4.1.1.17]
        L-ornithine = putrescine + CO(2).
          		 28 A0A0B0DX96 A0A3L6L1P4 I0GRF9 L8HNA3 N1P128 O22616 O50657 P00860 P07805 P08432
          (18 more...)
          Amino-acid racemase. [EC: 5.1.1.10]
          An L-amino acid = a D-amino acid.
            		 19 A0A0F6KE83 A0A0H2YJ65 A0A0H5UYP2 A0A0K9UXV2 A0A0L8RWP7 A0A0M1V677 A0A0U1R312 A0A2R4TWZ7 A0A2V4FB78 A0A3G5J9F1
            (9 more...)
            Carboxynorspermidine decarboxylase. [EC: 4.1.1.96]
            (1) Carboxynorspermidine = bis(3-aminopropyl)amine + CO(2). (2) Carboxyspermidine = spermidine + CO(2).
            • Part of a bacterial polyamine biosynthesis pathway.
            • The enzyme is essential for biofilm formation in the bacterium Vibrio cholerae.
            • The enzyme from Campylobacter jejuni only produces spermidine in vivo even though it shows activity with carboxynorspermidine in vitro.
            		 12 A0A0H3AGN6 A0A0H6AS28 A0A1J6UGJ2 A0A1L9L7P4 A0A1W6M2W1 A8FNH9 C3LMV0 C6YCI2 Q56575 Q5QCP2
            (2 more...)
            2-((L-alanin-3-ylcarbamoyl)methyl)-2-hydroxybutanedioate decarboxylase. [EC: 4.1.1.117]
            2-((L-alanin-3-ylcarbamoyl)methyl)-2-hydroxybutanedioate = 2-((2-aminoethylcarbamoyl)methyl)-2-hydroxybutanedioate + CO(2).
            • The enzyme, characterized from the bacterium Staphylococcus aureus, participates in the biosynthesis of the siderophore staphyloferrin B.
            		 6 A0A0H2X066 A0A0H2XH47 A0A0H3K696 A0A1E8X1N7 A0A380ECW1 Q2G1M6
            Lysine racemase. [EC: 5.1.1.5]
            L-lysine = D-lysine.
            • The enzyme is involved in a lysine catabolic pathway.
            		 3 D3L711 M4GGR9 Q04HB7
            Lysine decarboxylase. [EC: 4.1.1.18]
            L-lysine = cadaverine + CO(2).
            • Also acts on 5'-hydroxy-L-lysine.
            		 2 I0GRF9 O50657
            L-glutamyl-[BtrI acyl-carrier protein] decarboxylase. [EC: 4.1.1.95]
            L-glutamyl-[BtrI acyl-carrier protein] = 4-amino butanoyl-[BtrI acyl- carrier protein] + CO(2).
            • Catalyzes a step in the biosynthesis of the side chain of the aminoglycoside antibiotics of the butirosin family.
            • Has very low activity with substrates not bound to an acyl-carrier protein.
            		 1 Q2L4H3