The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DNA-binding pseudobarrel domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: Auxin response factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 15 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
29 O23661 (/ISS) P93022 (/ISS) P93024 (/ISS) P93024 (/ISS) Q84WU6 (/ISS) Q8L7G0 (/ISS) Q8L7G0 (/ISS) Q8RYC8 (/ISS) Q93YR9 (/ISS) Q94JM3 (/ISS)
(19 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
16 P93022 (/IPI) P93024 (/IPI) P93024 (/IPI) Q8L7G0 (/IPI) Q8L7G0 (/IPI) Q8RYC8 (/IPI) Q93YR9 (/IPI) Q94JM3 (/IPI) Q9C5W9 (/IPI) Q9C5W9 (/IPI)
(6 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
4 P93022 (/IDA) Q8L7G0 (/IDA) Q8L7G0 (/IDA) Q8RYC8 (/IDA)
MiRNA binding GO:0035198
Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
4 Q93YR9 (/ISS) Q9SKN5 (/ISS) Q9SKN5 (/ISS) Q9SKN5 (/ISS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 P93024 (/IPI) P93024 (/IPI) Q8L7G0 (/IPI) Q8L7G0 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
4 Q9FGV1 (/IPI) Q9FGV1 (/IPI) Q9XED8 (/IPI) Q9XED8 (/IPI)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
3 O23661 (/TAS) Q9FGV1 (/TAS) Q9FGV1 (/TAS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
2 O23661 (/IDA) Q94JM3 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q8RYC8 (/IDA) Q94JM3 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 P93024 (/IDA) P93024 (/IDA)
Proximal promoter sequence-specific DNA binding GO:0000987
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q84WU6 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 O23661 (/ISS)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q2LAJ3 (/IPI)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 Q2LAJ3 (/IPI)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
1 Q8RYC8 (/IDA)

There are 61 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
6 Q84WU6 (/TAS) Q9C7I9 (/TAS) Q9C8N7 (/TAS) Q9C8N9 (/TAS) Q9LP07 (/TAS) Q9LQE8 (/TAS)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
5 P93024 (/IEP) P93024 (/IEP) Q8L7G0 (/IEP) Q8L7G0 (/IEP) Q93YR9 (/IEP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
5 P93022 (/IMP) Q8RYC8 (/IMP) Q9FGV1 (/IMP) Q9FGV1 (/IMP) Q9ZTX8 (/IMP)
Flower development GO:0009908
The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
5 P93024 (/IGI) P93024 (/IGI) Q9FGV1 (/IGI) Q9FGV1 (/IGI) Q9ZTX8 (/IGI)
Pattern specification process GO:0007389
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.
4 Q93YR9 (/IDA) Q9SKN5 (/IDA) Q9SKN5 (/IDA) Q9SKN5 (/IDA)
Root cap development GO:0048829
The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.
4 Q93YR9 (/IGI) Q9SKN5 (/IGI) Q9SKN5 (/IGI) Q9SKN5 (/IGI)
Root cap development GO:0048829
The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.
4 Q93YR9 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
4 Q93YR9 (/IGI) Q9SKN5 (/IGI) Q9SKN5 (/IGI) Q9SKN5 (/IGI)
Auxin-activated signaling pathway GO:0009734
A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.
3 Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Abscisic acid-activated signaling pathway GO:0009738
A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
3 Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Response to carbohydrate GO:0009743
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
3 Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Fruit development GO:0010154
The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.
3 Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Regulation of anthocyanin biosynthetic process GO:0031540
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
3 Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Leaf development GO:0048366
The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.
3 Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Petal development GO:0048441
The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.
3 Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Sepal development GO:0048442
The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure.
3 Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Developmental growth GO:0048589
The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
3 Q9SKN5 (/IMP) Q9SKN5 (/IMP) Q9SKN5 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 P93024 (/IEP) P93024 (/IEP)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
2 P93024 (/IGI) P93024 (/IGI)
Longitudinal axis specification GO:0009942
The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.
2 P93024 (/IMP) P93024 (/IMP)
Vegetative phase change GO:0010050
Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.
2 O23661 (/IGI) Q9ZTX9 (/IGI)
Xylem and phloem pattern formation GO:0010051
The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.
2 P93024 (/IMP) P93024 (/IMP)
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
2 Q8L7G0 (/IGI) Q8L7G0 (/IGI)
Abaxial cell fate specification GO:0010158
The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
2 O23661 (/IGI) Q9ZTX9 (/IGI)
Leaf vascular tissue pattern formation GO:0010305
Vascular tissue pattern formation as it occurs in the leaf of vascular plants.
2 P93024 (/IGI) P93024 (/IGI)
Lateral root formation GO:0010311
The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.
2 P93022 (/IGI) Q8RYC8 (/IGI)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q8L7G0 (/IEP) Q8L7G0 (/IEP)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
2 P93024 (/IGI) P93024 (/IGI)
Leaf development GO:0048366
The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.
2 P93022 (/IGI) Q8RYC8 (/IGI)
Meristem development GO:0048507
The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.
2 P93024 (/IGI) P93024 (/IGI)
Lateral root development GO:0048527
The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.
2 P93022 (/IGI) Q8RYC8 (/IGI)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q94JM3 (/IMP)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
1 Q84WU6 (/IMP)
Gravitropism GO:0009630
The orientation of plant parts under the stimulation of gravity.
1 P93022 (/TAS)
Phototropism GO:0009638
The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.
1 P93022 (/IMP)
Anatomical structure morphogenesis GO:0009653
The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
1 Q84WU6 (/IMP)
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
1 P93022 (/IGI)
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
1 Q8RYC8 (/IMP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
1 O23661 (/ISS)
Auxin-activated signaling pathway GO:0009734
A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.
1 Q84WU6 (/TAS)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 Q94JM3 (/IMP)
Blue light signaling pathway GO:0009785
The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.
1 P93022 (/IMP)
Fruit ripening GO:0009835
An aging process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.
1 Q2LAJ3 (/IEP)
Fruit ripening, climacteric GO:0009836
A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset.
1 Q2LAJ3 (/IMP)
Auxin metabolic process GO:0009850
The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth.
1 O23661 (/TAS)
Positive regulation of flower development GO:0009911
Any process that activates or increases the frequency, rate or extent of flower development.
1 Q2LAJ3 (/IEP)
Positive regulation of flower development GO:0009911
Any process that activates or increases the frequency, rate or extent of flower development.
1 Q94JM3 (/IMP)
Fruit dehiscence GO:0010047
The process leading to the spontaneous opening of the fruit permitting the escape of seeds.
1 Q94JM3 (/IMP)
Vegetative phase change GO:0010050
Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.
1 O23661 (/IMP)
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
1 Q94JM3 (/IMP)
Pollen wall assembly GO:0010208
The formation of reticulate pollen wall pattern consisting of two layers, exine and intine.
1 Q84WU6 (/IMP)
Floral organ abscission GO:0010227
The controlled shedding of floral organs.
1 Q94JM3 (/IMP)
Floral meristem determinacy GO:0010582
The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).
1 O23661 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q94JM3 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 Q94JM3 (/TAS)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P93022 (/IMP)
Plant ovule development GO:0048481
The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
1 Q94JM3 (/IMP)
Adventitious root development GO:0048830
The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.
1 Q84WU6 (/IMP)
Callose deposition in cell wall GO:0052543
Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
1 Q84WU6 (/IMP)
Positive regulation of response to water deprivation GO:1902584
Any process that activates or increases the frequency, rate or extent of response to water deprivation.
1 O23661 (/IMP)
Positive regulation of potassium ion import across plasma membrane GO:1903288
Any process that activates or increases the frequency, rate or extent of potassium ion import across the plasma membrane.
1 Q94JM3 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 O23661 (/IDA) P93022 (/IDA) Q8RYC8 (/IDA) Q93YR9 (/IDA) Q94JM3 (/IDA) Q9ZTX8 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 P93024 (/ISS) P93024 (/ISS) Q8L7G0 (/ISS) Q8L7G0 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 P93024 (/IDA) P93024 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q8RYC8 (/TAS)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
1 Q9ZPY6 (/IDA)