The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 95: Zinc metalloprotease

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Metalloendopeptidase activity GO:0004222
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
80 P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA)
(70 more)
Anti-sigma factor antagonist activity GO:0043856
The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity.
80 P0AEH1 (/IMP) P0AEH1 (/IMP) P0AEH1 (/IMP) P0AEH1 (/IMP) P0AEH1 (/IMP) P0AEH1 (/IMP) P0AEH1 (/IMP) P0AEH1 (/IMP) P0AEH1 (/IMP) P0AEH1 (/IMP)
(70 more)
Antisigma factor binding GO:0045152
Interacting selectively and non-covalently with an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.
80 P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA)
(70 more)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Proteolysis GO:0006508
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
62 D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP)
(52 more)
Response to temperature stimulus GO:0009266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
62 D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP)
(52 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
62 D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP)
(52 more)
Cellular stress response to acid chemical GO:0097533
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
62 D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP) D0ZKX9 (/IMP)
(52 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
80 P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA)
(70 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
80 P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA) P0AEH1 (/IDA)
(70 more)