The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: microtubule-associated serine/threonine-protein ki...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 O60307 (/IPI) Q60592 (/IPI) Q6P0Q8 (/IPI) Q9R1L5 (/IPI) Q9Y2H9 (/IPI)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
4 Q6P0Q8 (/ISS) Q810W7 (/ISS) Q9R1L5 (/ISS) Q9Y2H9 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
4 Q6P0Q8 (/ISS) Q810W7 (/ISS) Q9R1L5 (/ISS) Q9Y2H9 (/ISS)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
3 Q810W7 (/ISS) Q9R1L5 (/ISS) Q9Y2H9 (/ISS)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2 Q60592 (/IDA) Q9R1L5 (/IDA)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2 Q810W7 (/ISS) Q9Y2H9 (/ISS)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 Q60592 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 Q9VUQ9 (/IMP)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q60592 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
1 Q9VUQ9 (/ISM)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q60592 (/IDA)
Phosphatase binding GO:0019902
Interacting selectively and non-covalently with any phosphatase.
1 Q6P0Q8 (/IPI)
Phosphatase binding GO:0019902
Interacting selectively and non-covalently with any phosphatase.
1 Q60592 (/ISO)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
4 Q6P0Q8 (/ISS) Q810W7 (/ISS) Q9R1L5 (/ISS) Q9Y2H9 (/ISS)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
3 Q810W7 (/ISS) Q9R1L5 (/ISS) Q9Y2H9 (/ISS)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
2 Q810W7 (/ISS) Q9Y2H9 (/ISS)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2 Q9R1L5 (/IMP) Q9Y2H9 (/IMP)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q60592 (/IDA)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q9VUQ9 (/IMP)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
1 Q9R1L5 (/IDA)
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
1 Q9VUQ9 (/IMP)
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
1 Q9VUQ9 (/IMP)
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
1 Q9VUQ9 (/IMP)
Cellularization GO:0007349
The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development.
1 Q9VUQ9 (/IMP)
Dosage compensation by hyperactivation of X chromosome GO:0009047
Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.
1 Q9VUQ9 (/IGI)
Lipid droplet transport along microtubule GO:0031887
The directed movement of a lipid droplet along a microtubule, mediated by motor proteins.
1 Q9VUQ9 (/IMP)
Wing disc development GO:0035220
Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
1 Q9VUQ9 (/IMP)
Regulation of interleukin-12 biosynthetic process GO:0045075
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12.
1 Q60592 (/IDA)
Regulation of interleukin-12 biosynthetic process GO:0045075
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12.
1 Q6P0Q8 (/ISS)
Positive regulation of cell size GO:0045793
Any process that increases cell size.
1 Q9VUQ9 (/IGI)
Spermatid differentiation GO:0048515
The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
1 Q60592 (/IDA)
Spermatid differentiation GO:0048515
The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
1 Q6P0Q8 (/ISS)
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
1 Q9VUQ9 (/IMP)
Positive regulation of ATP-dependent microtubule motor activity, minus-end-directed GO:2000579
Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.
1 Q9VUQ9 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
2 Q810W7 (/ISS) Q9Y2H9 (/ISS)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 Q810W7 (/ISS) Q9Y2H9 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9VUQ9 (/IDA)
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
1 Q60592 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9R1L5 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q9R1L5 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 Q9R1L5 (/IDA)