The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 76: Protein lin-7 homolog

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
31 O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI)
(21 more)
L27 domain binding GO:0097016
Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.
26 O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI) O14910 (/IPI)
(16 more)
L27 domain binding GO:0097016
Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.
2 Q8JZS0 (/ISO) Q8JZS0 (/ISO)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 Q9Z250 (/IPI)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Exocytosis GO:0006887
A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell.
26 O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS)
(16 more)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
26 O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS)
(16 more)
Protein-containing complex assembly GO:0065003
The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex.
26 O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS)
(16 more)
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
3 Q9VBY7 (/NAS) Q9VBY7 (/NAS) Q9VBY7 (/NAS)
Border follicle cell migration GO:0007298
The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
3 Q9VBY7 (/IMP) Q9VBY7 (/IMP) Q9VBY7 (/IMP)
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
3 Q9VBY7 (/IMP) Q9VBY7 (/IMP) Q9VBY7 (/IMP)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission.
2 Q8JZS0 (/IGI) Q8JZS0 (/IGI)
Synaptic vesicle transport GO:0048489
The directed movement of synaptic vesicles.
2 Q8JZS0 (/IMP) Q8JZS0 (/IMP)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
2 Q8JZS0 (/IDA) Q8JZS0 (/IDA)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
26 O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS) O14910 (/TAS)
(16 more)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
26 O14910 (/HDA) O14910 (/HDA) O14910 (/HDA) O14910 (/HDA) O14910 (/HDA) O14910 (/HDA) O14910 (/HDA) O14910 (/HDA) O14910 (/HDA) O14910 (/HDA)
(16 more)
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
3 Q8JZS0 (/IDA) Q8JZS0 (/IDA) Q9Z250 (/IDA)
Subapical complex GO:0035003
The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
3 Q9VBY7 (/IDA) Q9VBY7 (/IDA) Q9VBY7 (/IDA)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
3 Q9VBY7 (/IDA) Q9VBY7 (/IDA) Q9VBY7 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 Q8JZS0 (/IDA) Q8JZS0 (/IDA)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
1 Q9Z250 (/IDA)