The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 161: Synaptojanin-2-binding protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | P57105 (/IPI) P57105 (/IPI) P57105 (/IPI) P57105 (/IPI) P57105 (/IPI) Q9D6K5 (/IPI) Q9WVJ4 (/IPI) |
|
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | Q9WVJ4 (/IPI) |
|
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
|
1 | Q9D6K5 (/ISO) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of endothelial cell proliferation GO:0001937
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
|
5 | P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) |
|
Regulation of Notch signaling pathway GO:0008593
Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
|
5 | P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) |
|
Negative regulation of endothelial cell migration GO:0010596
Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
5 | P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) |
|
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
5 | P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) |
|
Negative regulation of ERK1 and ERK2 cascade GO:0070373
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
5 | P57105 (/IDA) P57105 (/IDA) P57105 (/IDA) P57105 (/IDA) P57105 (/IDA) |
|
Negative regulation of sprouting angiogenesis GO:1903671
Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.
|
5 | P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) P57105 (/IMP) |
|
Negative regulation of endothelial cell proliferation GO:0001937
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
|
4 | Q3T0C9 (/ISS) Q3T0C9 (/ISS) Q9D6K5 (/ISS) Q9WVJ4 (/ISS) |
|
Regulation of Notch signaling pathway GO:0008593
Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
|
4 | Q3T0C9 (/ISS) Q3T0C9 (/ISS) Q9D6K5 (/ISS) Q9WVJ4 (/ISS) |
|
Negative regulation of endothelial cell migration GO:0010596
Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
4 | Q3T0C9 (/ISS) Q3T0C9 (/ISS) Q9D6K5 (/ISS) Q9WVJ4 (/ISS) |
|
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
4 | Q3T0C9 (/ISS) Q3T0C9 (/ISS) Q9D6K5 (/ISS) Q9WVJ4 (/ISS) |
|
Negative regulation of ERK1 and ERK2 cascade GO:0070373
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
4 | Q3T0C9 (/ISS) Q3T0C9 (/ISS) Q9D6K5 (/ISS) Q9WVJ4 (/ISS) |
|
Negative regulation of sprouting angiogenesis GO:1903671
Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.
|
4 | Q3T0C9 (/ISS) Q3T0C9 (/ISS) Q9D6K5 (/ISS) Q9WVJ4 (/ISS) |
|
Negative regulation of endothelial cell proliferation GO:0001937
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
|
1 | Q9D6K5 (/ISO) |
|
Protein targeting GO:0006605
The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
|
1 | Q9D6K5 (/IDA) |
|
Cytoplasm organization GO:0007028
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9D6K5 (/ISO) |
|
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
|
1 | Q9D6K5 (/IDA) |
|
Regulation of Notch signaling pathway GO:0008593
Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
|
1 | Q9D6K5 (/ISO) |
|
Negative regulation of endothelial cell migration GO:0010596
Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | Q9D6K5 (/ISO) |
|
Negative regulation of angiogenesis GO:0016525
Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
|
1 | Q9D6K5 (/ISO) |
|
Regulation of endocytosis GO:0030100
Any process that modulates the frequency, rate or extent of endocytosis.
|
1 | Q9D6K5 (/IDA) |
|
Intracellular distribution of mitochondria GO:0048312
Any process that establishes the spatial arrangement of mitochondria within the cell.
|
1 | Q9WVJ4 (/IDA) |
|
Intracellular distribution of mitochondria GO:0048312
Any process that establishes the spatial arrangement of mitochondria within the cell.
|
1 | Q9D6K5 (/ISO) |
|
Negative regulation of ERK1 and ERK2 cascade GO:0070373
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q9D6K5 (/ISO) |
|
Negative regulation of sprouting angiogenesis GO:1903671
Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.
|
1 | Q9D6K5 (/ISO) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
5 | P57105 (/IDA) P57105 (/IDA) P57105 (/IDA) P57105 (/IDA) P57105 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | Q9D6K5 (/ISO) |
|
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
1 | Q9D6K5 (/ISO) |
|
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9WVJ4 (/IDA) |
|
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q9D6K5 (/ISO) |