The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Pelota, domain A
".
FunFam 5: Protein DOM34 homolog
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
|
5 | P33309 (/IDA) P33309 (/IDA) P33309 (/IDA) P33309 (/IDA) P33309 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | P33309 (/IPI) P33309 (/IPI) P33309 (/IPI) P33309 (/IPI) P33309 (/IPI) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Ribosome disassembly GO:0032790
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
|
5 | P33309 (/IDA) P33309 (/IDA) P33309 (/IDA) P33309 (/IDA) P33309 (/IDA) |
|
Ribosome disassembly GO:0032790
The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
|
5 | P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) |
|
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
|
5 | P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) |
|
Nonfunctional rRNA decay GO:0070651
An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.
|
5 | P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) |
|
Nuclear-transcribed mRNA catabolic process, no-go decay GO:0070966
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.
|
5 | P33309 (/IGI) P33309 (/IGI) P33309 (/IGI) P33309 (/IGI) P33309 (/IGI) |
|
Nuclear-transcribed mRNA catabolic process, no-go decay GO:0070966
The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.
|
5 | P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) P33309 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | P33309 (/HDA) P33309 (/HDA) P33309 (/HDA) P33309 (/HDA) P33309 (/HDA) |
|
Dom34-Hbs1 complex GO:1990533
A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.
|
5 | P33309 (/IDA) P33309 (/IDA) P33309 (/IDA) P33309 (/IDA) P33309 (/IDA) |