The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
CAP Gly-rich-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: CAP-Gly domain-containing linker protein 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Ganglioside binding GO:0035594
Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 B9EHT4 (/IPI) B9EHT4 (/IPI) Q96DZ5 (/IPI) Q96DZ5 (/IPI) Q96DZ5 (/IPI) Q96DZ5 (/IPI) Q96DZ5 (/IPI)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
5 Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
5 Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP)
Ganglioside binding GO:0035594
Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.
5 Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Ganglioside binding GO:0035594
Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)

There are 27 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
13 D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS) Q96DZ5 (/ISS) Q96DZ5 (/ISS)
(3 more)
Positive regulation of glucose transmembrane transport GO:0010828
Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
13 D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS) Q96DZ5 (/ISS) Q96DZ5 (/ISS)
(3 more)
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
13 D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS) Q96DZ5 (/ISS) Q96DZ5 (/ISS)
(3 more)
Positive regulation of protein localization to plasma membrane GO:1903078
Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.
13 D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS) Q96DZ5 (/ISS) Q96DZ5 (/ISS)
(3 more)
Peptidyl-L-cysteine S-palmitoylation GO:0018230
The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Negative regulation of microtubule polymerization GO:0031115
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Membrane biogenesis GO:0044091
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Positive regulation of endocytosis GO:0045807
Any process that activates or increases the frequency, rate or extent of endocytosis.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Chaperone-mediated protein transport GO:0072321
The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Regulation of tumor necrosis factor-mediated signaling pathway GO:0010803
Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
5 Q96DZ5 (/TAS) Q96DZ5 (/TAS) Q96DZ5 (/TAS) Q96DZ5 (/TAS) Q96DZ5 (/TAS)
Peptidyl-L-cysteine S-palmitoylation GO:0018230
The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.
5 Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP)
Negative regulation of microtubule polymerization GO:0031115
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.
5 Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
5 Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP)
Membrane biogenesis GO:0044091
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.
5 Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP)
Positive regulation of endocytosis GO:0045807
Any process that activates or increases the frequency, rate or extent of endocytosis.
5 Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP)
Chaperone-mediated protein transport GO:0072321
The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.
5 Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
2 B9EHT4 (/IDA) B9EHT4 (/IDA)
Positive regulation of glucose transmembrane transport GO:0010828
Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 B9EHT4 (/IMP) B9EHT4 (/IMP)
Peptidyl-L-cysteine S-palmitoylation GO:0018230
The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Negative regulation of microtubule polymerization GO:0031115
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Membrane biogenesis GO:0044091
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
2 B9EHT4 (/IEP) B9EHT4 (/IEP)
Positive regulation of endocytosis GO:0045807
Any process that activates or increases the frequency, rate or extent of endocytosis.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Chaperone-mediated protein transport GO:0072321
The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Positive regulation of protein localization to plasma membrane GO:1903078
Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.
2 B9EHT4 (/IDA) B9EHT4 (/IDA)

There are 20 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
13 D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS) Q96DZ5 (/ISS) Q96DZ5 (/ISS)
(3 more)
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Trans-Golgi network membrane GO:0032588
The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Recycling endosome membrane GO:0055038
The lipid bilayer surrounding a recycling endosome.
10 B9EHT4 (/ISS) B9EHT4 (/ISS) D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 D2HFU1 (/ISS) D4A507 (/ISS) D4A507 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) E1BAL0 (/ISS) Q5R686 (/ISS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
7 B9EHT4 (/IDA) B9EHT4 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 Q96DZ5 (/TAS) Q96DZ5 (/TAS) Q96DZ5 (/TAS) Q96DZ5 (/TAS) Q96DZ5 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP)
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
5 Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA)
Trans-Golgi network membrane GO:0032588
The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
5 Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA)
Trans-Golgi network membrane GO:0032588
The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
5 Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP) Q96DZ5 (/IMP)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
5 Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA)
Recycling endosome membrane GO:0055038
The lipid bilayer surrounding a recycling endosome.
5 Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA) Q96DZ5 (/IDA)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
2 B9EHT4 (/IDA) B9EHT4 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Trans-Golgi network membrane GO:0032588
The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)
Recycling endosome membrane GO:0055038
The lipid bilayer surrounding a recycling endosome.
2 B9EHT4 (/ISO) B9EHT4 (/ISO)