CATH Superfamily 2.20.70.10
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 76: Polyglutamine-binding protein 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
8 | A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A2T806 (/ISS) A2T806 (/ISS) A2T806 (/ISS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
5 | O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) |
|
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
|
5 | O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
5 | O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | O60828 (/IPI) O60828 (/IPI) O60828 (/IPI) O60828 (/IPI) O60828 (/IPI) |
|
Ribonucleoprotein complex binding GO:0043021
Interacting selectively and non-covalently with any complex of RNA and protein.
|
5 | O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
|
13 |
A1YFA7 (/ISS)
A1YFA7 (/ISS)
A1YFA7 (/ISS)
A1YFA7 (/ISS)
A1YFA7 (/ISS)
A2T806 (/ISS)
A2T806 (/ISS)
A2T806 (/ISS)
O60828 (/ISS)
O60828 (/ISS)
(3 more) |
|
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
|
8 | A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A2T806 (/ISS) A2T806 (/ISS) A2T806 (/ISS) |
|
Activation of innate immune response GO:0002218
Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
|
8 | A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A2T806 (/ISS) A2T806 (/ISS) A2T806 (/ISS) |
|
Positive regulation of defense response to virus by host GO:0002230
Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
|
8 | A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A2T806 (/ISS) A2T806 (/ISS) A2T806 (/ISS) |
|
Positive regulation of type I interferon production GO:0032481
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
8 | A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A2T806 (/ISS) A2T806 (/ISS) A2T806 (/ISS) |
|
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
8 | A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A2T806 (/ISS) A2T806 (/ISS) A2T806 (/ISS) |
|
Cellular response to exogenous dsRNA GO:0071360
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
|
8 | A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A1YFA7 (/ISS) A2T806 (/ISS) A2T806 (/ISS) A2T806 (/ISS) |
|
Alternative mRNA splicing, via spliceosome GO:0000380
The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
|
5 | O60828 (/IMP) O60828 (/IMP) O60828 (/IMP) O60828 (/IMP) O60828 (/IMP) |
|
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
5 | O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) |
|
Activation of innate immune response GO:0002218
Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
|
5 | O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) |
|
Positive regulation of defense response to virus by host GO:0002230
Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
|
5 | O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) |
|
Positive regulation of type I interferon production GO:0032481
Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
|
5 | O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) |
|
Regulation of RNA splicing GO:0043484
Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
|
5 | O60828 (/IMP) O60828 (/IMP) O60828 (/IMP) O60828 (/IMP) O60828 (/IMP) |
|
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
5 | O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) |
|
Cellular response to exogenous dsRNA GO:0071360
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
|
5 | O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
13 |
A1YFA7 (/ISS)
A1YFA7 (/ISS)
A1YFA7 (/ISS)
A1YFA7 (/ISS)
A1YFA7 (/ISS)
A2T806 (/ISS)
A2T806 (/ISS)
A2T806 (/ISS)
O60828 (/ISS)
O60828 (/ISS)
(3 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
10 | A0A0S2Z4V5 (/IDA) A0A0S2Z4V5 (/IDA) A0A0S2Z4V5 (/IDA) A0A0S2Z4V5 (/IDA) A0A0S2Z4V5 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) |
|
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
|
10 | A0A0S2Z4V5 (/IDA) A0A0S2Z4V5 (/IDA) A0A0S2Z4V5 (/IDA) A0A0S2Z4V5 (/IDA) A0A0S2Z4V5 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) O60828 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
5 | O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) O60828 (/TAS) |