The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
WRKY domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: WRKY transcription factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 12 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
26 O22921 (/ISS) O22921 (/ISS) O65590 (/ISS) O65590 (/ISS) P59583 (/ISS) P59583 (/ISS) Q8S8P5 (/ISS) Q8S8P5 (/ISS) Q8S8P5 (/ISS) Q93WU7 (/ISS)
(16 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 O22921 (/IPI) O22921 (/IPI) O65590 (/IPI) O65590 (/IPI) P59583 (/IPI) P59583 (/IPI) Q8S8P5 (/IPI) Q8S8P5 (/IPI) Q8S8P5 (/IPI) Q9C5T3 (/IPI)
(2 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
8 Q8S8P5 (/IPI) Q8S8P5 (/IPI) Q8S8P5 (/IPI) Q93WV0 (/IPI) Q93WV0 (/IPI) Q9SI37 (/IPI) Q9SI37 (/IPI) Q9XI90 (/IPI)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
5 Q8S8P5 (/IDA) Q8S8P5 (/IDA) Q8S8P5 (/IDA) Q9SI37 (/IDA) Q9SI37 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
4 Q8S8P5 (/IDA) Q8S8P5 (/IDA) Q8S8P5 (/IDA) Q9XI90 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 Q554C5 (/ISS) Q554C5 (/ISS) Q9XI90 (/ISS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 Q9SI37 (/IMP) Q9SI37 (/IMP)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 Q9SI37 (/IDA) Q9SI37 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 Q554C5 (/ISS) Q554C5 (/ISS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
1 Q93WU7 (/IMP)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q9XI90 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 Q9XI90 (/IPI)

There are 38 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
7 O22921 (/IEP) O22921 (/IEP) O65590 (/IEP) O65590 (/IEP) Q8S8P5 (/IEP) Q8S8P5 (/IEP) Q8S8P5 (/IEP)
Epidermal cell fate specification GO:0009957
The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
6 Q9ZUU0 (/IMP) Q9ZUU0 (/IMP) Q9ZUU0 (/IMP) Q9ZUU0 (/IMP) Q9ZUU0 (/IMP) Q9ZUU0 (/IMP)
Seed coat development GO:0010214
The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.
6 Q9ZUU0 (/IMP) Q9ZUU0 (/IMP) Q9ZUU0 (/IMP) Q9ZUU0 (/IMP) Q9ZUU0 (/IMP) Q9ZUU0 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
6 O22921 (/IMP) O22921 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q9C5T3 (/IMP)
Cellular heat acclimation GO:0070370
Any process that increases heat tolerance of a cell in response to high temperatures.
6 O22921 (/IMP) O22921 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q9C5T3 (/IMP)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
5 O22921 (/IEP) O22921 (/IEP) Q8S8P5 (/IEP) Q8S8P5 (/IEP) Q8S8P5 (/IEP)
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
5 O22921 (/IMP) O22921 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
5 Q6IEQ7 (/IDA) Q93WV0 (/IDA) Q93WV0 (/IDA) Q9SI37 (/IDA) Q9SI37 (/IDA)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
4 O65590 (/IGI) O65590 (/IGI) Q9FG77 (/IGI) Q9FG77 (/IGI)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
3 Q8S8P5 (/IEP) Q8S8P5 (/IEP) Q8S8P5 (/IEP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
3 Q8S8P5 (/IEP) Q8S8P5 (/IEP) Q8S8P5 (/IEP)
Systemic acquired resistance GO:0009627
The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.
3 Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP)
Camalexin biosynthetic process GO:0010120
The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.
3 Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP)
Response to chitin GO:0010200
A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.
3 Q8S8P5 (/IEP) Q8S8P5 (/IEP) Q8S8P5 (/IEP)
Positive regulation of autophagy GO:0010508
Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
3 Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
3 Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP)
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
3 Q8S8P5 (/IMP) Q8S8P5 (/IMP) Q8S8P5 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9FG77 (/IMP) Q9FG77 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 Q554C5 (/ISS) Q554C5 (/ISS)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
2 Q93WV0 (/IEP) Q93WV0 (/IEP)
Response to salicylic acid GO:0009751
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
2 Q9SI37 (/IEP) Q9SI37 (/IEP)
Pollen germination GO:0009846
The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.
2 O65590 (/IMP) O65590 (/IMP)
Salicylic acid mediated signaling pathway GO:0009863
A series of molecular signals mediated by salicylic acid.
2 Q9SI37 (/IEP) Q9SI37 (/IEP)
Longitudinal axis specification GO:0009942
The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.
2 Q9FG77 (/IMP) Q9FG77 (/IMP)
Response to 1-aminocyclopropane-1-carboxylic acid GO:0009961
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.
2 Q93WV0 (/IEP) Q93WV0 (/IEP)
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
2 Q9FG77 (/IMP) Q9FG77 (/IMP)
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
1 Q9XI90 (/IDA)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 Q6IEQ7 (/IDA)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 Q6B6R4 (/IEP)
Response to gibberellin GO:0009739
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
1 Q6IEQ7 (/IDA)
Response to salicylic acid GO:0009751
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
1 Q9XI90 (/IDA)
Response to jasmonic acid GO:0009753
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
1 Q9XI90 (/IDA)
Response to jasmonic acid GO:0009753
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
1 Q6B6R4 (/IEP)
Negative regulation of abscisic acid-activated signaling pathway GO:0009788
Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.
1 Q6IEQ7 (/IMP)
Negative regulation of gibberellic acid mediated signaling pathway GO:0009938
Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity.
1 Q6IEQ7 (/IMP)
Regulation of defense response GO:0031347
Any process that modulates the frequency, rate or extent of a defense response.
1 Q93WU7 (/IMP)
Regulation of defense response to fungus GO:1900150
Any process that modulates the frequency, rate or extent of defense response to fungus.
1 Q9XI90 (/IMP)
Negative regulation of defense response to bacterium GO:1900425
Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium.
1 Q9XI90 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
11 O22921 (/IDA) O22921 (/IDA) O65590 (/IDA) O65590 (/IDA) Q6IEQ7 (/IDA) Q8S8P5 (/IDA) Q8S8P5 (/IDA) Q8S8P5 (/IDA) Q9SI37 (/IDA) Q9SI37 (/IDA)
(1 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q554C5 (/IC) Q554C5 (/IC)