The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 21: Multifunctional methyltransferase subunit trm112

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Maturation of LSU-rRNA GO:0000470
Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.
9 P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP)
TRNA modification GO:0006400
The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
9 P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS)
Peptidyl-glutamine methylation GO:0018364
The addition of a methyl group to a glutamine residue in a protein.
9 P53738 (/IDA) P53738 (/IDA) P53738 (/IDA) P53738 (/IDA) P53738 (/IDA) P53738 (/IDA) P53738 (/IDA) P53738 (/IDA) P53738 (/IDA)
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
9 P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP)
Maturation of SSU-rRNA GO:0030490
Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.
9 P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP)
Ribosomal large subunit biogenesis GO:0042273
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
9 P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP)
Ribosomal small subunit biogenesis GO:0042274
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
9 P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP)
RRNA (guanine-N7)-methylation GO:0070476
The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.
9 P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP) P53738 (/IMP)
Peptidyl-glutamine methylation GO:0018364
The addition of a methyl group to a glutamine residue in a protein.
1 Q09723 (/ISO)
TRNA methylation GO:0030488
The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
1 Q09723 (/ISO)
Regulation of cytoplasmic translation GO:2000765
Any process that modulates the frequency, rate or extent of cytoplasmic translation.
1 Q09723 (/ISO)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) Q09723 (/HDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
9 P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA) P53738 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS) P53738 (/TAS)
ERF1 methyltransferase complex GO:0035657
A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.
9 P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI)
TRNA (m2G10) methyltransferase complex GO:0043528
A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p.
9 P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI) P53738 (/IPI)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q09723 (/HDA)
ERF1 methyltransferase complex GO:0035657
A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.
1 Q09723 (/ISO)
TRNA (m2G10) methyltransferase complex GO:0043528
A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p.
1 Q09723 (/ISO)