The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Putative transcription factor IIIB 90 kDa subunit

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q92994 (/IPI) Q92994 (/IPI) Q92994 (/IPI) Q9VEL2 (/IPI)
RNA polymerase III type 3 promoter sequence-specific DNA binding GO:0001006
Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.
2 Q9P6R0 (/IDA) Q9VEL2 (/IDA)
RNA polymerase III general transcription initiation factor activity GO:0000995
An activity that contributes to transcription start site selection and transcription initiation of genes transcribed by RNA polymerase III. Factors required for RNA polymerase III transcription initiation include TFIIIA, TFIIIB and TFIIIC.
1 Q9P6R0 (/IMP)
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
1 Q9VEL2 (/IPI)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thrombocyte differentiation GO:0002574
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.
3 A0A2R8QF19 (/IMP) Q5TZ89 (/IMP) Q6P9Z3 (/IMP)
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
3 Q92994 (/TAS) Q92994 (/TAS) Q92994 (/TAS)
Transcription initiation from RNA polymerase III promoter GO:0006384
Any process involved in the assembly of the RNA polymerase III preinitiation complex (PIC) at an RNA polymerase III promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
3 Q92994 (/TAS) Q92994 (/TAS) Q92994 (/TAS)
RRNA transcription GO:0009303
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.
3 Q92994 (/TAS) Q92994 (/TAS) Q92994 (/TAS)
TRNA transcription GO:0009304
The synthesis of transfer RNA (tRNA) from a DNA template.
3 Q92994 (/TAS) Q92994 (/TAS) Q92994 (/TAS)
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
3 A0A2R8QF19 (/IMP) Q5TZ89 (/IMP) Q6P9Z3 (/IMP)
Myeloid cell differentiation GO:0030099
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
3 B8A4L9 (/IMP) F1R9S3 (/IMP) Q802Z8 (/IMP)
Neutrophil differentiation GO:0030223
The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.
3 B8A4L9 (/IMP) F1R9S3 (/IMP) Q802Z8 (/IMP)
Transcription initiation from RNA polymerase III promoter GO:0006384
Any process involved in the assembly of the RNA polymerase III preinitiation complex (PIC) at an RNA polymerase III promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
2 P43072 (/ISS) P43072 (/ISS)
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
1 Q9VEL2 (/IDA)
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
1 Q9VEL2 (/IPI)
Regulation of mRNA stability GO:0043488
Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
1 Q8CFK2 (/IMP)
Positive regulation of transcription by RNA polymerase III GO:0045945
Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III.
1 Q9P6R0 (/IC)
Positive regulation of transcription by RNA polymerase III GO:0045945
Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III.
1 Q9P6R0 (/IMP)
Positive regulation of transcription by RNA polymerase III GO:0045945
Any process that activates or increases the frequency, rate or extent of transcription mediated by RNA polymerase III.
1 Q8CFK2 (/ISO)
RNA polymerase III preinitiation complex assembly GO:0070898
The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter.
1 Q9P6R0 (/ISO)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription factor TFIIIB complex GO:0000126
A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF.
3 Q92994 (/NAS) Q92994 (/NAS) Q92994 (/NAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 Q92994 (/TAS) Q92994 (/TAS) Q92994 (/TAS)
Transcription factor TFIIIB complex GO:0000126
A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF.
2 Q9P6R0 (/IDA) Q9VEL2 (/IDA)
Transcription factor TFIIIB complex GO:0000126
A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF.
2 P43072 (/ISS) P43072 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9P6R0 (/HDA)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 Q9VEL2 (/IPI)