The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.

A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme.

The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.

Any process that activates or increases the frequency, rate or extent of DNA repair.

A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.

A process in which a protein is transported to, or maintained in, a location within a Cajal body.

Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.

Any process that activates or increases the frequency, rate or extent of double-strand break repair.

Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.

Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.

The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.

The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.

The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.

A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme.

A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme.

The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.

The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.

Any process that activates or increases the frequency, rate or extent of DNA repair.

Any process that activates or increases the frequency, rate or extent of DNA repair.

Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.

A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.

A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.

A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.

A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.

A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.

Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.

Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.

A process in which a protein is transported to, or maintained in, a location within a Cajal body.

A process in which a protein is transported to, or maintained in, a location within a Cajal body.

A process in which a protein is transported to, or maintained in, a location within a Cajal body.

Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.

Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.

Any process that activates or increases the frequency, rate or extent of double-strand break repair.

Any process that activates or increases the frequency, rate or extent of double-strand break repair.

Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.

Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.

Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.

A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.

A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.

That part of the nuclear content other than the chromosomes or the nucleolus.

That part of the nuclear content other than the chromosomes or the nucleolus.

Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.

Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.

A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.

A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.

Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.

Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.

A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.

A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.