The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
YVTN repeat-like/Quinoprotein amine dehydrogenase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 359: Eukaryotic translation initiation factor 2A

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
1 Q9BY44 (/IMP)
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
1 Q8BJW6 (/ISO)
TRNA binding GO:0000049
Interacting selectively and non-covalently with transfer RNA.
1 Q8BJW6 (/ISS)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
1 Q9BY44 (/IMP)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
1 Q8BJW6 (/ISO)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
1 Q8BJW6 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9BY44 (/IPI)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
1 Q9BY44 (/IMP)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
1 Q8BJW6 (/ISO)
Ribosome binding GO:0043022
Interacting selectively and non-covalently with any part of a ribosome.
1 Q8BJW6 (/ISS)
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
1 Q9BY44 (/HDA)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
1 Q8BJW6 (/IDA)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 Q9BY44 (/IMP)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 Q8BJW6 (/ISO)
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
1 Q8BJW6 (/ISS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 Q8BJW6 (/IDA)
Positive regulation of signal transduction GO:0009967
Any process that activates or increases the frequency, rate or extent of signal transduction.
1 Q8BJW6 (/IDA)
SREBP signaling pathway GO:0032933
A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.
1 Q8BJW6 (/IDA)
Ribosome assembly GO:0042255
The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
1 Q9BY44 (/IMP)
Ribosome assembly GO:0042255
The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
1 Q8BJW6 (/ISO)
Ribosome assembly GO:0042255
The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
1 Q8BJW6 (/ISS)
Response to amino acid starvation GO:1990928
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
1 D3ZUV3 (/IDA)
Response to amino acid starvation GO:1990928
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
1 Q8BJW6 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q9BY44 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9BY44 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8BJW6 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8BJW6 (/ISS)
Eukaryotic translation initiation factor 2 complex GO:0005850
Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.
1 Q9BY44 (/IDA)
Eukaryotic translation initiation factor 2 complex GO:0005850
Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.
1 Q8BJW6 (/ISO)
Eukaryotic translation initiation factor 2 complex GO:0005850
Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.
1 Q8BJW6 (/ISS)
Blood microparticle GO:0072562
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
1 Q9BY44 (/HDA)