The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TolB, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 31: B-box type zinc finger protein ncl-1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Translation repressor activity GO:0030371
Antagonizes ribosome-mediated translation of mRNA into a polypeptide.
3 P34611 (/IMP) Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
MRNA 3'-UTR binding GO:0003730
Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q8MQJ9 (/IPI) Q8MQJ9 (/IPI)
Translation regulator activity GO:0045182
Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
2 Q8MQJ9 (/TAS) Q8MQJ9 (/TAS)

There are 31 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of translation GO:0006417
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 Q8MQJ9 (/TAS) Q8MQJ9 (/TAS)
Neuroblast fate determination GO:0007400
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Ganglion mother cell fate determination GO:0007402
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Neuroblast proliferation GO:0007405
The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Negative regulation of neuroblast proliferation GO:0007406
Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.
2 Q8MQJ9 (/IGI) Q8MQJ9 (/IGI)
Negative regulation of neuroblast proliferation GO:0007406
Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Ventral cord development GO:0007419
The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.
2 Q8MQJ9 (/HMP) Q8MQJ9 (/HMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Asymmetric cell division GO:0008356
The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
RRNA transcription GO:0009303
The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Neuroblast differentiation GO:0014016
The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Neuroblast development GO:0014019
The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Negative regulation of translation GO:0017148
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Segmentation GO:0035282
The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 Q8MQJ9 (/HMP) Q8MQJ9 (/HMP)
Regulation of neurogenesis GO:0050767
Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.
2 Q8MQJ9 (/IGI) Q8MQJ9 (/IGI)
Regulation of neurogenesis GO:0050767
Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Asymmetric neuroblast division resulting in ganglion mother cell formation GO:0055060
Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Regulation of synaptic vesicle endocytosis GO:1900242
Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis.
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)
Regulation of neuroblast proliferation GO:1902692
Any process that modulates the frequency, rate or extent of neuroblast proliferation.
2 Q8MQJ9 (/IGI) Q8MQJ9 (/IGI)
Negative regulation of transcription by RNA polymerase I GO:0016479
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I.
1 P34611 (/IMP)
Negative regulation of transcription by RNA polymerase III GO:0016480
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase III.
1 P34611 (/IMP)
Nucleologenesis GO:0017126
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.
1 P34611 (/IMP)
Protein localization to cell cortex GO:0072697
A process in which a protein is transported to, or maintained in, the cell cortex.
1 P34611 (/IMP)
Negative regulation of ribosome biogenesis GO:0090071
Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
1 P34611 (/IMP)
Regulation of establishment of cell polarity GO:2000114
Any process that modulates the frequency, rate or extent of establishment of cell polarity.
1 P34611 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P34611 (/IDA) Q8MQJ9 (/IDA) Q8MQJ9 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q8MQJ9 (/IDA) Q8MQJ9 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 Q8MQJ9 (/IDA) Q8MQJ9 (/IDA)
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
2 Q8MQJ9 (/IDA) Q8MQJ9 (/IDA)
Basal cortex GO:0045180
The region that lies just beneath the plasma membrane on the basal edge of a cell.
2 Q8MQJ9 (/IDA) Q8MQJ9 (/IDA)
Cell cortex region GO:0099738
The complete extent of cell cortex that underlies some some region of the plasma membrane
2 Q8MQJ9 (/IMP) Q8MQJ9 (/IMP)