The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TolB, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 120: Transmembrane serine/threonine-protein kinase D

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
8 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA)
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
8 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P9WI79 (/IPI) P9WI79 (/IPI) P9WI79 (/IPI) P9WI79 (/IPI) P9WI79 (/IPI) P9WI79 (/IPI) P9WI79 (/IPI) P9WI79 (/IPI)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
8 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
8 P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP) P9WI79 (/IMP)
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
8 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA)
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
8 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA)
Positive regulation of catalytic activity GO:0043085
Any process that activates or increases the activity of an enzyme.
8 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA)
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
8 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA)
Negative regulation of fatty acid biosynthetic process GO:0045717
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
8 P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA) P9WI79 (/IDA)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
8 P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
8 P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
8 P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
8 P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA) P9WI79 (/HDA)