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CATH Superfamily 2.10.25.10

Laminin

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 655: Complement component C1q receptor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Complement component C1q binding GO:0001849
Interacting selectively and non-covalently with the C1q component of the classical complement cascade.
 2 Q9NPY3 (/IDA) Q9NPY3 (/IDA)
Complement component C1q binding GO:0001849
Interacting selectively and non-covalently with the C1q component of the classical complement cascade.
 2 O89103 (/ISO) O89103 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 2 Q9NPY3 (/IPI) Q9NPY3 (/IPI)
Signaling receptor activity GO:0038023
Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
 2 Q9NPY3 (/NAS) Q9NPY3 (/NAS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
 4 O89103 (/ISS) O89103 (/ISS) Q9ET61 (/ISS) Q9ET61 (/ISS)
Phagocytosis GO:0006909
A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
 2 Q9NPY3 (/NAS) Q9NPY3 (/NAS)
Macrophage activation GO:0042116
A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
 2 Q9NPY3 (/NAS) Q9NPY3 (/NAS)
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
 2 Q9NPY3 (/TAS) Q9NPY3 (/TAS)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
 2 Q9NPY3 (/IDA) Q9NPY3 (/IDA)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
 2 O89103 (/ISO) O89103 (/ISO)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 4 O89103 (/IDA) O89103 (/IDA) Q9NPY3 (/IDA) Q9NPY3 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 2 O89103 (/ISO) O89103 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 2 Q9NPY3 (/TAS) Q9NPY3 (/TAS)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
 2 O89103 (/IDA) O89103 (/IDA)
Secretory granule membrane GO:0030667
The lipid bilayer surrounding a secretory granule.
 2 Q9NPY3 (/TAS) Q9NPY3 (/TAS)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
 2 O89103 (/IDA) O89103 (/IDA)
Specific granule membrane GO:0035579
The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
 2 Q9NPY3 (/TAS) Q9NPY3 (/TAS)
Tertiary granule membrane GO:0070821
The lipid bilayer surrounding a tertiary granule.
 2 Q9NPY3 (/TAS) Q9NPY3 (/TAS)
Ficolin-1-rich granule membrane GO:0101003
The lipid bilayer surrounding a ficolin-1-rich granule.
 2 Q9NPY3 (/TAS) Q9NPY3 (/TAS)