The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Laminin
".
FunFam 470: Stabilin 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Low-density lipoprotein particle receptor activity GO:0005041
Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein particle into the cell via endocytosis.
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
Scavenger receptor activity GO:0005044
Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, amyloid-beta fibrils, and advanced glycation end products (AGEs).
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
Hyaluronic acid binding GO:0005540
Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
Hyaluronic acid binding GO:0005540
Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
|
2 | Q8R4U0 (/ISS) Q8R4U0 (/ISS) |
|
Low-density lipoprotein particle binding GO:0030169
Interacting selectively and non-covalently with a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm.
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
Hyaluronic acid binding GO:0005540
Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
|
1 | Q8CFM6 (/IDA) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
5 | A0A2R8RX33 (/IGI) C6GHV6 (/IGI) E7EYE0 (/IGI) F1R1R8 (/IGI) F6P8Y7 (/IGI) |
|
Blood vessel development GO:0001568
The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
|
5 | A0A2R8RX33 (/IMP) C6GHV6 (/IMP) E7EYE0 (/IMP) F1R1R8 (/IMP) F6P8Y7 (/IMP) |
|
Blood vessel endothelial cell differentiation GO:0060837
The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.
|
5 | A0A2R8RX33 (/IMP) C6GHV6 (/IMP) E7EYE0 (/IMP) F1R1R8 (/IMP) F6P8Y7 (/IMP) |
|
Positive regulation of lymphangiogenesis GO:1901492
Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.
|
5 | A0A2R8RX33 (/IMP) C6GHV6 (/IMP) E7EYE0 (/IMP) F1R1R8 (/IMP) F6P8Y7 (/IMP) |
|
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
|
3 | Q8CFM6 (/ISS) Q8R4U0 (/ISS) Q8R4U0 (/ISS) |
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
2 | Q8R4U0 (/ISS) Q8R4U0 (/ISS) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
1 | Q8CFM6 (/IDA) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | Q8R4U0 (/ISO) Q8R4U0 (/ISO) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
2 | Q8R4U0 (/ISS) Q8R4U0 (/ISS) |
|
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
|
1 | Q8CFM6 (/IDA) |