The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 290: EGF-containing fibulin-like extracellular matrix p...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 O95967 (/IPI) O95967 (/IPI) O95967 (/IPI) O95967 (/IPI) Q9WVJ9 (/IPI) Q9WVJ9 (/IPI) Q9WVJ9 (/IPI) Q9WVJ9 (/IPI)
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
4 O95967 (/RCA) O95967 (/RCA) O95967 (/RCA) O95967 (/RCA)
Extracellular matrix structural constituent GO:0005201
The action of a molecule that contributes to the structural integrity of the extracellular matrix.
4 O95967 (/TAS) O95967 (/TAS) O95967 (/TAS) O95967 (/TAS)
Extracellular matrix constituent conferring elasticity GO:0030023
A component of the extracellular matrix that enables the matrix to recoil after transient stretching.
4 Q9WVJ9 (/RCA) Q9WVJ9 (/RCA) Q9WVJ9 (/RCA) Q9WVJ9 (/RCA)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Elastic fiber assembly GO:0048251
Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.
4 Q9WVJ9 (/IMP) Q9WVJ9 (/IMP) Q9WVJ9 (/IMP) Q9WVJ9 (/IMP)
Artery development GO:0060840
The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.
4 Q9WVJ9 (/IMP) Q9WVJ9 (/IMP) Q9WVJ9 (/IMP) Q9WVJ9 (/IMP)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
8 O95967 (/HDA) O95967 (/HDA) O95967 (/HDA) O95967 (/HDA) Q9WVJ9 (/HDA) Q9WVJ9 (/HDA) Q9WVJ9 (/HDA) Q9WVJ9 (/HDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
4 O95967 (/TAS) O95967 (/TAS) O95967 (/TAS) O95967 (/TAS)
Basement membrane GO:0005604
A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
4 O95967 (/TAS) O95967 (/TAS) O95967 (/TAS) O95967 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
4 Q9WVJ9 (/HDA) Q9WVJ9 (/HDA) Q9WVJ9 (/HDA) Q9WVJ9 (/HDA)
Extracellular matrix GO:0031012
A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues.
4 Q9WVJ9 (/TAS) Q9WVJ9 (/TAS) Q9WVJ9 (/TAS) Q9WVJ9 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
4 O95967 (/HDA) O95967 (/HDA) O95967 (/HDA) O95967 (/HDA)
Extracellular vesicle GO:1903561
Any vesicle that is part of the extracellular region.
4 O95967 (/HDA) O95967 (/HDA) O95967 (/HDA) O95967 (/HDA)