The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 267: pro-neuregulin-3, membrane-bound isoform

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
2 P56975 (/NAS) P56975 (/NAS)
Transmembrane receptor protein tyrosine kinase activator activity GO:0030297
Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase.
2 P56975 (/NAS) P56975 (/NAS)
Receptor tyrosine kinase binding GO:0030971
Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
2 P56975 (/NAS) P56975 (/NAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 O35181 (/IPI)
Chemorepellent activity GO:0045499
Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.
1 O35181 (/IDA)

There are 10 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
2 P56975 (/NAS) P56975 (/NAS)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
2 P56975 (/IMP) P56975 (/IMP)
Pattern specification process GO:0007389
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.
1 O35181 (/IMP)
Chemorepulsion involved in interneuron migration from the subpallium to the cortex GO:0021842
The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex.
1 O35181 (/IMP)
Mammary gland development GO:0030879
The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
1 O35181 (/IDA)
Mammary gland development GO:0030879
The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
1 O35181 (/IMP)
Intracellular signal transduction GO:0035556
The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
1 O35181 (/IDA)
Modulation of chemical synaptic transmission GO:0050804
Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
1 O35181 (/ISO)
Mammary placode formation GO:0060596
The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.
1 O35181 (/IMP)
Negative regulation of neuron migration GO:2001223
Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.
1 O35181 (/IDA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 P56975 (/NAS) P56975 (/NAS)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P56975 (/NAS) P56975 (/NAS)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
2 P56975 (/IMP) P56975 (/IMP)
Glutamatergic synapse GO:0098978
A synapse that uses glutamate as a neurotransmitter.
1 O35181 (/ISO)