The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Laminin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 235: Prostaglandin G/H synthase 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
9 O02768 (/ISS) O19183 (/ISS) O62698 (/ISS) O62725 (/ISS) P27607 (/ISS) P35354 (/ISS) P35355 (/ISS) P70682 (/ISS) P79208 (/ISS)
Prostaglandin-endoperoxide synthase activity GO:0004666
Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
8 O02768 (/ISS) O19183 (/ISS) O62698 (/ISS) O62725 (/ISS) P27607 (/ISS) P35355 (/ISS) P70682 (/ISS) P79208 (/ISS)
Peroxidase activity GO:0004601
Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.
7 A0A2R8QJU6 (/IDA) F1R0R6 (/IDA) Q1JPW2 (/IDA) Q5RI06 (/IDA) Q6P4V3 (/IDA) Q8JH43 (/IDA) Q8JH44 (/IDA)
Prostaglandin-endoperoxide synthase activity GO:0004666
Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
5 A0A2R8QJU6 (/IMP) F1R0R6 (/IMP) P05979 (/IMP) Q1JPW2 (/IMP) Q8JH44 (/IMP)
Prostaglandin-endoperoxide synthase activity GO:0004666
Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
3 P23219 (/IDA) P35354 (/IDA) Q05769 (/IDA)
Prostaglandin-endoperoxide synthase activity GO:0004666
Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P35354 (/IPI) P35355 (/IPI) Q05769 (/IPI)
Heme binding GO:0020037
Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
2 P05979 (/IDA) Q05769 (/IDA)
Peroxidase activity GO:0004601
Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.
1 P35354 (/NAS)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 P05979 (/IDA)
Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
1 P35355 (/IDA)
Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen GO:0016702
Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
1 Q05769 (/ISO)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 P35354 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 Q05769 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 P05979 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q05769 (/IPI)

There are 154 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Prostaglandin biosynthetic process GO:0001516
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
11 O02768 (/ISS) O19183 (/ISS) O62698 (/ISS) O62725 (/ISS) P05979 (/ISS) P23219 (/ISS) P27607 (/ISS) P35354 (/ISS) P70682 (/ISS) P79208 (/ISS)
(1 more)
Regulation of blood pressure GO:0008217
Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
10 O02768 (/ISS) O19183 (/ISS) P05979 (/ISS) P23219 (/ISS) P27607 (/ISS) P35354 (/ISS) P35355 (/ISS) P70682 (/ISS) P79208 (/ISS) Q63921 (/ISS)
Cyclooxygenase pathway GO:0019371
The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.
8 O02768 (/ISS) O19183 (/ISS) O62698 (/ISS) O62725 (/ISS) P27607 (/ISS) P35355 (/ISS) P70682 (/ISS) P79208 (/ISS)
Regulation of neuroinflammatory response GO:0150077
Any process that modulates the frequency, rate or extent of neuroinflammatory response.
8 O02768 (/ISS) O19183 (/ISS) O62698 (/ISS) O62725 (/ISS) P35354 (/ISS) P35355 (/ISS) P70682 (/ISS) P79208 (/ISS)
Prostaglandin biosynthetic process GO:0001516
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
7 F1MNI5 (/IMP) F1MNI5 (/IMP) O62698 (/IMP) P22437 (/IMP) P22437 (/IMP) P35355 (/IMP) Q63921 (/IMP)
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
7 A0A2R8QJU6 (/IDA) F1R0R6 (/IDA) Q1JPW2 (/IDA) Q5RI06 (/IDA) Q6P4V3 (/IDA) Q8JH43 (/IDA) Q8JH44 (/IDA)
Exocrine pancreas development GO:0031017
The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
6 A0A2R8QJU6 (/IMP) F1R0R6 (/IMP) Q1JPW2 (/IMP) Q6P4V3 (/IMP) Q8JH43 (/IMP) Q8JH44 (/IMP)
Pronephros development GO:0048793
The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
6 A0A2R8QJU6 (/IMP) F1R0R6 (/IMP) Q1JPW2 (/IMP) Q6P4V3 (/IMP) Q8JH43 (/IMP) Q8JH44 (/IMP)
Embryonic liver development GO:1990402
The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.
6 A0A2R8QJU6 (/IMP) F1R0R6 (/IMP) Q1JPW2 (/IMP) Q6P4V3 (/IMP) Q8JH43 (/IMP) Q8JH44 (/IMP)
Vasculogenesis GO:0001570
The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
4 A0A2R8QJU6 (/IMP) F1R0R6 (/IMP) Q1JPW2 (/IMP) Q8JH44 (/IMP)
Kidney development GO:0001822
The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
4 A0A2R8QJU6 (/IMP) F1R0R6 (/IMP) Q1JPW2 (/IMP) Q8JH44 (/IMP)
Meiotic spindle organization GO:0000212
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.
3 F1MNI5 (/IMP) F1MNI5 (/IMP) O62698 (/IMP)
Prostaglandin biosynthetic process GO:0001516
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Ovarian cumulus expansion GO:0001550
Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.
3 F1MNI5 (/IMP) F1MNI5 (/IMP) O62698 (/IMP)
Positive regulation of protein phosphorylation GO:0001934
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
3 F1MNI5 (/IMP) F1MNI5 (/IMP) O62698 (/IMP)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Regulation of blood pressure GO:0008217
Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
3 P22437 (/IMP) P22437 (/IMP) Q05769 (/IMP)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Cyclooxygenase pathway GO:0019371
The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.
3 P23219 (/IDA) P35354 (/IDA) Q05769 (/IDA)
Cyclooxygenase pathway GO:0019371
The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Keratinocyte differentiation GO:0030216
The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.
3 P22437 (/NAS) P22437 (/NAS) Q05769 (/NAS)
Maintenance of permeability of blood-brain barrier GO:0035633
Preserving the permeability barrier between the blood and the brain in a stable functional or structural state. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Positive regulation of embryonic development GO:0040019
Any process that activates or increases the frequency, rate or extent of embryonic development.
3 F1MNI5 (/IMP) F1MNI5 (/IMP) O62698 (/IMP)
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
3 P22437 (/IGI) P22437 (/IGI) Q05769 (/IGI)
Positive regulation of vasoconstriction GO:0045907
Any process that activates or increases the frequency, rate or extent of vasoconstriction.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Positive regulation of smooth muscle contraction GO:0045987
Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Cellular response to interleukin-1 GO:0071347
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
3 F1MNI5 (/IMP) F1MNI5 (/IMP) O62698 (/IMP)
Negative regulation of blood vessel diameter GO:0097756
Any process that decreases the diameter of blood vessels.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Positive regulation of oocyte maturation GO:1900195
Any process that activates or increases the frequency, rate or extent of oocyte maturation.
3 F1MNI5 (/IMP) F1MNI5 (/IMP) O62698 (/IMP)
Positive regulation of meiotic cell cycle process involved in oocyte maturation GO:1904146
Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
3 F1MNI5 (/IMP) F1MNI5 (/IMP) O62698 (/IMP)
Prostaglandin metabolic process GO:0006693
The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
2 P22437 (/IMP) P22437 (/IMP)
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
2 P35355 (/IMP) Q05769 (/IMP)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
2 P35355 (/IEP) Q63921 (/IEP)
Learning GO:0007612
Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
2 P35355 (/IMP) Q63921 (/IMP)
Memory GO:0007613
The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
2 P35355 (/IMP) Q63921 (/IMP)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
2 P35355 (/IEP) Q63921 (/IEP)
Negative regulation of norepinephrine secretion GO:0010700
Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.
2 P22437 (/ISO) P22437 (/ISO)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
2 P35355 (/IMP) Q63921 (/IMP)
Cyclooxygenase pathway GO:0019371
The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.
2 P23219 (/TAS) P35354 (/TAS)
Positive regulation of fever generation GO:0031622
Any process that activates or increases the frequency, rate, or extent of fever generation.
2 P35355 (/IDA) Q05769 (/IDA)
Negative regulation of epinephrine secretion GO:0032811
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.
2 P22437 (/ISO) P22437 (/ISO)
Maintenance of permeability of blood-brain barrier GO:0035633
Preserving the permeability barrier between the blood and the brain in a stable functional or structural state. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
2 P35355 (/IMP) Q63921 (/IMP)
Positive regulation of vasoconstriction GO:0045907
Any process that activates or increases the frequency, rate or extent of vasoconstriction.
2 P35355 (/IMP) Q63921 (/IMP)
Positive regulation of smooth muscle contraction GO:0045987
Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.
2 P35355 (/IMP) Q63921 (/IMP)
Decidualization GO:0046697
The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
2 P35355 (/IMP) Q05769 (/IMP)
Response to steroid hormone GO:0048545
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
2 Q6P4V3 (/IEP) Q8JH43 (/IEP)
Response to fatty acid GO:0070542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
2 P35355 (/IEP) Q63921 (/IEP)
Negative regulation of blood vessel diameter GO:0097756
Any process that decreases the diameter of blood vessels.
2 P35355 (/IMP) Q63921 (/IMP)
Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress GO:1902219
Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.
2 Q05769 (/IMP) Q8SPQ9 (/IMP)
Prostaglandin biosynthetic process GO:0001516
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
1 Q05769 (/IDA)
Prostaglandin biosynthetic process GO:0001516
The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
1 P35354 (/NAS)
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
1 P35355 (/IMP)
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
1 Q05769 (/ISO)
Xenobiotic metabolic process GO:0006805
The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
1 P23219 (/TAS)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
1 P35355 (/IMP)
Inflammatory response GO:0006954
The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
1 Q05769 (/ISO)
Embryo implantation GO:0007566
Attachment of the blastocyst to the uterine lining.
1 Q05769 (/ISO)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 P35355 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 Q05769 (/ISO)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 P35355 (/IDA)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q05769 (/ISO)
Response to radiation GO:0009314
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
1 P35355 (/IEP)
Response to fructose GO:0009750
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
1 P35355 (/IEP)
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
1 P35355 (/IEP)
Response to manganese ion GO:0010042
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
1 P35355 (/IEP)
Response to lithium ion GO:0010226
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
1 P35355 (/IEP)
Positive regulation of vascular endothelial growth factor production GO:0010575
Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.
1 P35355 (/IMP)
Positive regulation of vascular endothelial growth factor production GO:0010575
Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.
1 Q05769 (/ISO)
Positive regulation of vascular endothelial growth factor production GO:0010575
Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.
1 P35354 (/ISS)
Negative regulation of norepinephrine secretion GO:0010700
Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.
1 Q63921 (/IMP)
Positive regulation of cell death GO:0010942
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
1 P35355 (/IMP)
Positive regulation of cell death GO:0010942
Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
1 Q05769 (/ISO)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 P35355 (/IEP)
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 P35354 (/TAS)
Cyclooxygenase pathway GO:0019371
The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.
1 P05979 (/IMP)
Lipoxygenase pathway GO:0019372
The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.
1 P35354 (/TAS)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
1 P35355 (/IMP)
Bone mineralization GO:0030282
The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
1 Q05769 (/ISO)
Ovulation GO:0030728
The release of a mature ovum/oocyte from an ovary.
1 P35355 (/IMP)
Ovulation GO:0030728
The release of a mature ovum/oocyte from an ovary.
1 Q05769 (/ISO)
Positive regulation of prostaglandin biosynthetic process GO:0031394
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
1 Q8SPQ9 (/IDA)
Positive regulation of prostaglandin biosynthetic process GO:0031394
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
1 Q05769 (/IMP)
Positive regulation of prostaglandin biosynthetic process GO:0031394
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
1 P35354 (/NAS)
Positive regulation of fever generation GO:0031622
Any process that activates or increases the frequency, rate, or extent of fever generation.
1 Q05769 (/ISO)
Positive regulation of fever generation GO:0031622
Any process that activates or increases the frequency, rate, or extent of fever generation.
1 P35354 (/ISS)
Positive regulation of synaptic plasticity GO:0031915
A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
1 P35355 (/IMP)
Positive regulation of synaptic plasticity GO:0031915
A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
1 Q05769 (/ISO)
Negative regulation of synaptic transmission, dopaminergic GO:0032227
Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
1 P35355 (/IMP)
Negative regulation of synaptic transmission, dopaminergic GO:0032227
Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
1 Q05769 (/ISO)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 P35355 (/IEP)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P35355 (/IMP)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 Q05769 (/ISO)
Negative regulation of epinephrine secretion GO:0032811
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.
1 Q63921 (/IMP)
Positive regulation of peptidyl-serine phosphorylation GO:0033138
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
1 Q8SPQ9 (/IDA)
Positive regulation of peptidyl-serine phosphorylation GO:0033138
Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
1 Q05769 (/IMP)
Response to vitamin D GO:0033280
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
1 P35355 (/IEP)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 P35355 (/IMP)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 Q05769 (/ISO)
NAD biosynthesis via nicotinamide riboside salvage pathway GO:0034356
The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.
1 P35354 (/TAS)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 P35355 (/IEP)
Response to tumor necrosis factor GO:0034612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
1 P35355 (/IEP)
Cellular response to UV GO:0034644
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
1 P35355 (/IEP)
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
1 P35355 (/IMP)
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
1 Q05769 (/ISO)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P35355 (/IEP)
Hair cycle GO:0042633
The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
1 P35355 (/IEP)
Long-chain fatty acid biosynthetic process GO:0042759
The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
1 P35354 (/TAS)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 P35355 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
1 Q05769 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q8SPQ9 (/IDA)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 Q05769 (/IMP)
Negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154
Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
1 Q05769 (/IMP)
Positive regulation of nitric oxide biosynthetic process GO:0045429
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
1 P35355 (/IMP)
Positive regulation of nitric oxide biosynthetic process GO:0045429
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
1 Q05769 (/ISO)
Positive regulation of nitric oxide biosynthetic process GO:0045429
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
1 P35354 (/ISS)
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
1 P35355 (/IGI)
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
1 Q05769 (/ISO)
Negative regulation of smooth muscle contraction GO:0045986
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.
1 P35355 (/IMP)
Negative regulation of smooth muscle contraction GO:0045986
Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.
1 Q05769 (/ISO)
Decidualization GO:0046697
The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
1 Q05769 (/ISO)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
1 P35355 (/IMP)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
1 Q05769 (/ISO)
Regulation of inflammatory response GO:0050727
Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
1 P35354 (/NAS)
Brown fat cell differentiation GO:0050873
The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
1 Q05769 (/IMP)
Response to glucocorticoid GO:0051384
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
1 P35355 (/IEP)
Response to corticosterone GO:0051412
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
1 Q63921 (/IEP)
Negative regulation of calcium ion transport GO:0051926
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P35355 (/IMP)
Negative regulation of calcium ion transport GO:0051926
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q05769 (/ISO)
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
1 P35355 (/IMP)
Positive regulation of synaptic transmission, glutamatergic GO:0051968
Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
1 Q05769 (/ISO)
Cellular response to mechanical stimulus GO:0071260
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
1 P35355 (/IEP)
Cellular response to lead ion GO:0071284
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
1 P35355 (/IEP)
Cellular response to ATP GO:0071318
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
1 P35355 (/IEP)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P35354 (/IEP)
Cellular response to non-ionic osmotic stress GO:0071471
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.
1 Q8SPQ9 (/IDA)
Cellular response to non-ionic osmotic stress GO:0071471
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.
1 Q05769 (/IMP)
Cellular response to fluid shear stress GO:0071498
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.
1 Q05769 (/IDA)
Positive regulation of transforming growth factor beta production GO:0071636
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.
1 P35355 (/IMP)
Positive regulation of transforming growth factor beta production GO:0071636
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.
1 Q05769 (/ISO)
Positive regulation of transforming growth factor beta production GO:0071636
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.
1 P35354 (/ISS)
Positive regulation of cell migration involved in sprouting angiogenesis GO:0090050
Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
1 P35355 (/IMP)
Positive regulation of cell migration involved in sprouting angiogenesis GO:0090050
Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
1 Q05769 (/ISO)
Positive regulation of cell migration involved in sprouting angiogenesis GO:0090050
Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
1 P35354 (/ISS)
Positive regulation of fibroblast growth factor production GO:0090271
Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 P35355 (/IMP)
Positive regulation of fibroblast growth factor production GO:0090271
Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 Q05769 (/ISO)
Positive regulation of fibroblast growth factor production GO:0090271
Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 P35354 (/ISS)
Positive regulation of brown fat cell differentiation GO:0090336
Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
1 Q05769 (/IMP)
Positive regulation of brown fat cell differentiation GO:0090336
Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
1 P35354 (/ISS)
Positive regulation of platelet-derived growth factor production GO:0090362
Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 P35355 (/IMP)
Positive regulation of platelet-derived growth factor production GO:0090362
Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 Q05769 (/ISO)
Positive regulation of platelet-derived growth factor production GO:0090362
Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1 P35354 (/ISS)
Regulation of neuroinflammatory response GO:0150077
Any process that modulates the frequency, rate or extent of neuroinflammatory response.
1 Q05769 (/IDA)
Response to angiotensin GO:1990776
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.
1 P35355 (/IEP)

There are 21 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 O02768 (/ISS) O19183 (/ISS) P05979 (/ISS) P23219 (/ISS) P27607 (/ISS) P35354 (/ISS) P35355 (/ISS) P70682 (/ISS) P79208 (/ISS) Q63921 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 P22437 (/IDA) P22437 (/IDA) P23219 (/IDA) P35354 (/IDA) P35355 (/IDA) Q05769 (/IDA) Q63921 (/IDA) Q8SPQ9 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P22437 (/ISO) P22437 (/ISO) Q05769 (/ISO)
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins.
2 P22437 (/IDA) P22437 (/IDA)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
2 P22437 (/ISO) P22437 (/ISO)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
2 P23219 (/TAS) P35354 (/TAS)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 A0A087X296 (/IDA) P23219 (/IDA)
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
2 P22437 (/ISO) P22437 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
2 P35354 (/IDA) Q05769 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2 A0A087X296 (/IDA) P23219 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2 P22437 (/ISO) P22437 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2 P05979 (/ISS) Q63921 (/ISS)
Nuclear envelope GO:0005635
The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
1 Q63921 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q05769 (/IMP)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 P35354 (/IDA)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q05769 (/ISO)
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
1 P35354 (/TAS)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 P35355 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q05769 (/ISO)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q05769 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 P23219 (/HDA)