The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Cysteine Rich Protein
".
FunFam 45: LIM domain-binding protein 1 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 22 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
94 |
A0A0G2JVQ2 (/IPI)
A0A0G2JVQ2 (/IPI)
A0A0G2JVQ2 (/IPI)
A0A0G2JVQ2 (/IPI)
A0A0G2JVQ2 (/IPI)
A0A0G2JVQ2 (/IPI)
A0A0G2JVQ2 (/IPI)
A0A0G2JVQ2 (/IPI)
A0A0G2JVQ2 (/IPI)
A0A0G2JVQ2 (/IPI)
(84 more) |
|
LIM domain binding GO:0030274
Interacting selectively and non-covalently with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.
|
42 |
P70060 (/IPI)
P70060 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
(32 more) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
41 |
O55203 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
(31 more) |
|
LIM domain binding GO:0030274
Interacting selectively and non-covalently with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.
|
41 |
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
(31 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
25 |
P70060 (/IDA)
P70060 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(15 more) |
|
LIM domain binding GO:0030274
Interacting selectively and non-covalently with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.
|
24 |
O73715 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(14 more) |
|
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
|
23 |
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
(13 more) |
|
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
23 |
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(13 more) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
23 |
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(13 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
23 |
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
(13 more) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
23 |
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
(13 more) |
|
LIM domain binding GO:0030274
Interacting selectively and non-covalently with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.
|
23 |
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
(13 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
23 |
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
Q6NVL6 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(13 more) |
|
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
23 |
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
(13 more) |
|
RNA polymerase II activating transcription factor binding GO:0001102
Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
|
17 |
Q86U70 (/IPI)
Q86U70 (/IPI)
Q86U70 (/IPI)
Q86U70 (/IPI)
Q86U70 (/IPI)
Q86U70 (/IPI)
Q86U70 (/IPI)
Q86U70 (/IPI)
Q86U70 (/IPI)
Q86U70 (/IPI)
(7 more) |
|
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
|
17 |
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
(7 more) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
15 |
O43679 (/TAS)
O43679 (/TAS)
O43679 (/TAS)
O43679 (/TAS)
O43679 (/TAS)
O43679 (/TAS)
O43679 (/TAS)
O43679 (/TAS)
O43679 (/TAS)
O43679 (/TAS)
(5 more) |
|
Transcription coregulator activity GO:0003712
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to either activate or repress the transcription of specific genes. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class modulates interactions of DNA-binding transcription factor with other transcription coregulators.
|
11 |
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
(1 more) |
|
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.
|
4 | O18353 (/IPI) P70060 (/IPI) P70060 (/IPI) Q7KVG9 (/IPI) |
|
RNA polymerase II transcription factor binding GO:0001085
Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
|
2 | O18353 (/IPI) Q7KVG9 (/IPI) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | P70060 (/IPI) P70060 (/IPI) |
|
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
1 | O73715 (/IDA) |
There are 62 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
40 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(30 more) |
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
32 |
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
(22 more) |
|
Regulation of kinase activity GO:0043549
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
32 |
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
(22 more) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
25 |
O55203 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
(15 more) |
|
Hair follicle development GO:0001942
The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
|
24 |
O55203 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
(14 more) |
|
Epithelial structure maintenance GO:0010669
A tissue homeostatic process required for the maintenance of epithelial structure.
|
24 |
O55203 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
(14 more) |
|
Somatic stem cell population maintenance GO:0035019
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
|
24 |
O55203 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
(14 more) |
|
Regulation of kinase activity GO:0043549
Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
24 |
O55203 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(14 more) |
|
Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery GO:0000972
The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Gastrulation with mouth forming second GO:0001702
A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
23 |
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(13 more) |
|
Anterior/posterior axis specification GO:0009948
The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Wnt signaling pathway GO:0016055
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Cerebellum development GO:0021549
The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Cerebellar Purkinje cell differentiation GO:0021702
The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Cellular component assembly GO:0022607
The aggregation, arrangement and bonding together of a cellular component.
|
23 |
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
(13 more) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
23 |
P70662 (/IEP)
P70662 (/IEP)
P70662 (/IEP)
P70662 (/IEP)
P70662 (/IEP)
P70662 (/IEP)
P70662 (/IEP)
P70662 (/IEP)
P70662 (/IEP)
P70662 (/IEP)
(13 more) |
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
23 |
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(13 more) |
|
Regulation of DNA-templated transcription, elongation GO:0032784
Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Histone H3-K4 acetylation GO:0043973
The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Negative regulation of erythrocyte differentiation GO:0045647
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Positive regulation of cell adhesion GO:0045785
Any process that activates or increases the frequency, rate or extent of cell adhesion.
|
23 |
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
(13 more) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
23 |
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
(13 more) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
23 |
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
(13 more) |
|
Positive regulation of hemoglobin biosynthetic process GO:0046985
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Mesendoderm development GO:0048382
The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.
|
23 |
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
P70662 (/IMP)
(13 more) |
|
Regulation of focal adhesion assembly GO:0051893
Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions.
|
23 |
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(13 more) |
|
Primitive erythrocyte differentiation GO:0060319
Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.
|
23 |
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
(13 more) |
|
Head development GO:0060322
The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
|
23 |
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
P70662 (/IGI)
(13 more) |
|
Neuron differentiation GO:0030182
The process in which a relatively unspecialized cell acquires specialized features of a neuron.
|
22 |
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(12 more) |
|
Negative regulation of erythrocyte differentiation GO:0045647
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
|
22 |
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(12 more) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
18 |
Q6NVL6 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(8 more) |
|
Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery GO:0000972
The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.
|
17 |
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(7 more) |
|
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
|
17 |
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
(7 more) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
17 |
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
(7 more) |
|
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
|
17 |
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
Q86U70 (/NAS)
(7 more) |
|
Regulation of DNA-templated transcription, elongation GO:0032784
Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
|
17 |
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(7 more) |
|
Histone H3-K4 acetylation GO:0043973
The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone.
|
17 |
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(7 more) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
17 |
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
(7 more) |
|
Positive regulation of hemoglobin biosynthetic process GO:0046985
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
|
17 |
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(7 more) |
|
Regulation of focal adhesion assembly GO:0051893
Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions.
|
17 |
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(7 more) |
|
Regulation of hematopoietic stem cell differentiation GO:1902036
Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
|
17 |
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
Q86U70 (/TAS)
(7 more) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
11 |
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
F2Z5G6 (/IMP)
(1 more) |
|
Anterior/posterior axis specification GO:0009948
The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
5 | O42252 (/ISS) O42252 (/ISS) O42252 (/ISS) O42252 (/ISS) O42252 (/ISS) |
|
Wnt signaling pathway GO:0016055
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
|
5 | O42252 (/ISS) O42252 (/ISS) O42252 (/ISS) O42252 (/ISS) O42252 (/ISS) |
|
Blastoderm segmentation GO:0007350
The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.
|
2 | O18353 (/TAS) Q7KVG9 (/TAS) |
|
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Regulation of eclosion GO:0007563
Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Chaeta morphogenesis GO:0008407
The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Chaeta development GO:0022416
The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P70060 (/IDA) P70060 (/IDA) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P70060 (/IDA) P70060 (/IDA) |
|
Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Dendrite guidance GO:0070983
The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
2 | O18353 (/IMP) Q7KVG9 (/IMP) |
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
1 | O55203 (/IMP) |
|
Embryonic heart tube development GO:0035050
The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.
|
1 | Q7KVG9 (/IMP) |
|
Positive regulation of cellular component biogenesis GO:0044089
Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
|
1 | O55203 (/IGI) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q6NVL6 (/ISS) |
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
71 |
A0A0G2JVQ2 (/IDA)
A0A0G2JVQ2 (/IDA)
A0A0G2JVQ2 (/IDA)
A0A0G2JVQ2 (/IDA)
A0A0G2JVQ2 (/IDA)
A0A0G2JVQ2 (/IDA)
A0A0G2JVQ2 (/IDA)
A0A0G2JVQ2 (/IDA)
A0A0G2JVQ2 (/IDA)
A0A0G2JVQ2 (/IDA)
(61 more) |
|
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
41 |
O55203 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(31 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
40 |
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
P70662 (/TAS)
(30 more) |
|
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
|
32 |
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
O43679 (/ISS)
(22 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
25 |
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O55203 (/ISS)
Q1EQW7 (/ISS)
Q6NVL6 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(15 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
24 |
O55203 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
(14 more) |
|
Cell leading edge GO:0031252
The area of a motile cell closest to the direction of movement.
|
24 |
O55203 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(14 more) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
23 |
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
(13 more) |
|
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
23 |
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
(13 more) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
23 |
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
P70662 (/IDA)
(13 more) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
23 |
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
P70662 (/IPI)
(13 more) |
|
Beta-catenin-TCF complex GO:1990907
A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.
|
23 |
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
P70662 (/ISO)
(13 more) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
22 |
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
O42252 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
Q86U70 (/ISS)
(12 more) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
20 |
G5E9Y7 (/IDA)
G5E9Y7 (/IDA)
G5E9Y7 (/IDA)
G5E9Y7 (/IDA)
H0YA09 (/IDA)
O43679 (/IDA)
O43679 (/IDA)
O43679 (/IDA)
O43679 (/IDA)
O43679 (/IDA)
(10 more) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
20 |
G5E9Y7 (/IDA)
G5E9Y7 (/IDA)
G5E9Y7 (/IDA)
G5E9Y7 (/IDA)
H0YA09 (/IDA)
O43679 (/IDA)
O43679 (/IDA)
O43679 (/IDA)
O43679 (/IDA)
O43679 (/IDA)
(10 more) |
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
17 |
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
(7 more) |
|
Beta-catenin-TCF complex GO:1990907
A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.
|
17 |
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
Q86U70 (/IDA)
(7 more) |
|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | O55203 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O55203 (/ISO) |