The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 7: Protein farnesyltransferase subunit beta

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 P49356 (/IPI) P49356 (/IPI) P49356 (/IPI) P49356 (/IPI) Q02293 (/IPI) Q19752 (/IPI)
Protein farnesyltransferase activity GO:0004660
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
5 P49356 (/IDA) P49356 (/IDA) P49356 (/IDA) P49356 (/IDA) Q02293 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
4 P49356 (/IDA) P49356 (/IDA) P49356 (/IDA) P49356 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
3 P49355 (/ISS) Q02293 (/ISS) Q8K2I1 (/ISS)
Protein farnesyltransferase activity GO:0004660
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
2 P49355 (/ISS) Q8K2I1 (/ISS)
Farnesyltranstransferase activity GO:0004311
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
1 Q8K2I1 (/IMP)
Protein farnesyltransferase activity GO:0004660
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
1 Q8K2I1 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q8K2I1 (/ISO)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein farnesylation GO:0018343
The covalent attachment of a farnesyl group to a protein.
4 P49356 (/IDA) P49356 (/IDA) P49356 (/IDA) P49356 (/IDA)
Regulation of rhodopsin mediated signaling pathway GO:0022400
Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
4 P49356 (/TAS) P49356 (/TAS) P49356 (/TAS) P49356 (/TAS)
Protein farnesylation GO:0018343
The covalent attachment of a farnesyl group to a protein.
3 P49355 (/ISS) Q02293 (/ISS) Q8K2I1 (/ISS)
Cardiac ventricle development GO:0003231
The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
2 A0A2R8QF89 (/IMP) Q6IQG3 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 Q02293 (/IMP) Q8K2I1 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 Q8K2I1 (/ISO)
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 Q8K2I1 (/IMP)
Response to inorganic substance GO:0010035
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
1 Q02293 (/IMP)
Response to inorganic substance GO:0010035
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
1 Q8K2I1 (/ISO)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 Q02293 (/IMP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 Q8K2I1 (/ISO)
Protein farnesylation GO:0018343
The covalent attachment of a farnesyl group to a protein.
1 Q8K2I1 (/ISO)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 Q02293 (/IMP)
Response to cytokine GO:0034097
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 Q8K2I1 (/ISO)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
1 Q8K2I1 (/IMP)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
1 Q02293 (/IMP)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
1 Q8K2I1 (/ISO)
Regulation of fibroblast proliferation GO:0048145
Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
1 Q8K2I1 (/IMP)
Positive regulation of fibroblast proliferation GO:0048146
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
1 Q8K2I1 (/IMP)
Positive regulation of nitric-oxide synthase biosynthetic process GO:0051770
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.
1 Q02293 (/IMP)
Positive regulation of nitric-oxide synthase biosynthetic process GO:0051770
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.
1 Q8K2I1 (/ISO)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 P49356 (/TAS) P49356 (/TAS) P49356 (/TAS) P49356 (/TAS)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
4 P49356 (/IDA) P49356 (/IDA) P49356 (/IDA) P49356 (/IDA)
Protein farnesyltransferase complex GO:0005965
A protein complex that possesses protein farnesyltransferase activity.
4 P49356 (/IDA) P49356 (/IDA) P49356 (/IDA) P49356 (/IDA)
Protein farnesyltransferase complex GO:0005965
A protein complex that possesses protein farnesyltransferase activity.
3 P49355 (/ISS) Q02293 (/ISS) Q8K2I1 (/ISS)
Microtubule associated complex GO:0005875
Any multimeric complex connected to a microtubule.
1 Q8K2I1 (/ISO)
Protein farnesyltransferase complex GO:0005965
A protein complex that possesses protein farnesyltransferase activity.
1 Q8K2I1 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q02293 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q8K2I1 (/ISO)