The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: splicing factor, arginine/serine-rich 15

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
4 O95104 (/IDA) O95104 (/IDA) O95104 (/IDA) Q9UPN6 (/IDA)
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
4 A0A0B4LH25 (/ISS) A2VEJ9 (/ISS) A8DYK5 (/ISS) Q9W2K4 (/ISS)
RNA polymerase II C-terminal domain phosphoserine binding GO:1990269
Interacting selectively and non-covalently with phosphorylated serine residues in the C-terminal domain of RNA polymerase II.
4 O95104 (/IDA) O95104 (/IDA) O95104 (/IDA) Q9UPN6 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3 O95104 (/HDA) O95104 (/HDA) O95104 (/HDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3 Q63623 (/ISS) Q6DID3 (/ISS) Q7TSH6 (/ISS)
RNA polymerase II C-terminal domain phosphoserine binding GO:1990269
Interacting selectively and non-covalently with phosphorylated serine residues in the C-terminal domain of RNA polymerase II.
3 Q63623 (/ISS) Q6DID3 (/ISS) Q7TSH6 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9UPN6 (/IPI)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 Q7TSH6 (/ISO)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q63623 (/IMP)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q6DID3 (/ISO)
RNA polymerase core enzyme binding GO:0043175
Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.
1 Q9UPN6 (/IPI)
RNA polymerase core enzyme binding GO:0043175
Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.
1 Q6DID3 (/ISO)
RNA polymerase binding GO:0070063
Interacting selectively and non-covalently with an RNA polymerase molecule or complex.
1 Q63623 (/IPI)
RNA polymerase binding GO:0070063
Interacting selectively and non-covalently with an RNA polymerase molecule or complex.
1 Q6DID3 (/ISO)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled GO:2000805
Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
4 O95104 (/IDA) O95104 (/IDA) O95104 (/IDA) Q9UPN6 (/IDA)
Negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled GO:2000805
Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
3 Q63623 (/ISS) Q6DID3 (/ISS) Q7TSH6 (/ISS)
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
2 Q6DID3 (/ISO) Q7TSH6 (/ISO)
Positive regulation of DNA-templated transcription, elongation GO:0032786
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
2 Q63623 (/ISS) Q6DID3 (/ISS)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
1 Q63623 (/IMP)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
1 Q6DID3 (/ISO)
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
1 Q63623 (/IMP)
Positive regulation of DNA-templated transcription, elongation GO:0032786
Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
1 Q9UPN6 (/IDA)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 A0A0A0MT33 (/IDA) O95104 (/IDA) O95104 (/IDA) O95104 (/IDA) Q9UPN6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 O95104 (/IDA) O95104 (/IDA) O95104 (/IDA) Q9UPN6 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q6DID3 (/ISS) Q7TSH6 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q6DID3 (/ISO) Q7TSH6 (/ISO)
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
2 Q6DID3 (/ISS) Q9UPN6 (/ISS)
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
1 Q63623 (/IDA)
Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
1 Q6DID3 (/ISO)