The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Ankyrin repeat-containing domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 30: Kinase D-interacting substrate of 220 kDa

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 8 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein kinase regulator activity GO:0019887
Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.
5 A0A1Y7VMH7 (/ISO) A0A1Y7VNF8 (/ISO) B2RXL7 (/ISO) Q3V2X2 (/ISO) Q80SX9 (/ISO)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
5 A0A1Y7VMH7 (/ISO) A0A1Y7VNF8 (/ISO) B2RXL7 (/ISO) Q3V2X2 (/ISO) Q80SX9 (/ISO)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
5 A0A1Y7VMH7 (/ISO) A0A1Y7VNF8 (/ISO) B2RXL7 (/ISO) Q3V2X2 (/ISO) Q80SX9 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q9EQG6 (/IPI) Q9EQG6 (/IPI)
Protein kinase regulator activity GO:0019887
Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.
2 Q9EQG6 (/IDA) Q9EQG6 (/IDA)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
2 Q9EQG6 (/IDA) Q9EQG6 (/IDA)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
2 Q9EQG6 (/IDA) Q9EQG6 (/IDA)
PDZ domain binding GO:0030165
Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
1 Q9ULH0 (/ISS)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
5 A0A1Y7VMH7 (/IMP) A0A1Y7VNF8 (/IMP) B2RXL7 (/IMP) Q3V2X2 (/IMP) Q80SX9 (/IMP)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
5 A0A1Y7VMH7 (/ISO) A0A1Y7VNF8 (/ISO) B2RXL7 (/ISO) Q3V2X2 (/ISO) Q80SX9 (/ISO)
Nerve growth factor signaling pathway GO:0038180
A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
5 A0A1Y7VMH7 (/ISO) A0A1Y7VNF8 (/ISO) B2RXL7 (/ISO) Q3V2X2 (/ISO) Q80SX9 (/ISO)
Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
5 A0A1Y7VMH7 (/IMP) A0A1Y7VNF8 (/IMP) B2RXL7 (/IMP) Q3V2X2 (/IMP) Q80SX9 (/IMP)
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
5 A0A1Y7VMH7 (/ISO) A0A1Y7VNF8 (/ISO) B2RXL7 (/ISO) Q3V2X2 (/ISO) Q80SX9 (/ISO)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
2 Q9EQG6 (/IMP) Q9EQG6 (/IMP)
Nerve growth factor signaling pathway GO:0038180
A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 Q9EQG6 (/IDA) Q9EQG6 (/IDA)
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
2 Q9EQG6 (/IDA) Q9EQG6 (/IDA)
Activation of MAPKK activity GO:0000186
The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
1 Q9ULH0 (/TAS)
Positive regulation of neuron projection development GO:0010976
Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 Q9ULH0 (/ISS)
Nerve growth factor signaling pathway GO:0038180
A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 Q9ULH0 (/ISS)
Cellular response to nerve growth factor stimulus GO:1990090
A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
1 Q9ULH0 (/ISS)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
5 A0A1Y7VMH7 (/ISO) A0A1Y7VNF8 (/ISO) B2RXL7 (/ISO) Q3V2X2 (/ISO) Q80SX9 (/ISO)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
5 A0A1Y7VMH7 (/ISO) A0A1Y7VNF8 (/ISO) B2RXL7 (/ISO) Q3V2X2 (/ISO) Q80SX9 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 Q9EQG6 (/TAS) Q9EQG6 (/TAS) Q9ULH0 (/TAS)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
2 Q9EQG6 (/IDA) Q9EQG6 (/IDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
2 Q9EQG6 (/IDA) Q9EQG6 (/IDA)
Late endosome GO:0005770
A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
1 Q9ULH0 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q9ULH0 (/HDA)
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
1 Q9ULH0 (/ISS)