The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 819: Inscuteable

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 Q24367 (/IPI) Q94543 (/IPI) Q9W2R4 (/IPI)
Cytoskeletal adaptor activity GO:0008093
The binding activity of a molecule that brings together a cytoskeletal protein and one or more other molecules, permitting them to function in a coordinated way.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Cytoskeletal adaptor activity GO:0008093
The binding activity of a molecule that brings together a cytoskeletal protein and one or more other molecules, permitting them to function in a coordinated way.
3 Q24367 (/ISS) Q94543 (/ISS) Q9W2R4 (/ISS)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA localization GO:0006403
A process in which RNA is transported to, or maintained in, a specific location.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Neuroblast fate determination GO:0007400
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.
3 Q24367 (/IDA) Q94543 (/IDA) Q9W2R4 (/IDA)
Neuroblast fate determination GO:0007400
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.
3 Q24367 (/TAS) Q94543 (/TAS) Q9W2R4 (/TAS)
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Sensory organ development GO:0007423
The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.
3 Q24367 (/TAS) Q94543 (/TAS) Q9W2R4 (/TAS)
Somatic muscle development GO:0007525
The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Protein localization GO:0008104
Any process in which a protein is transported to, or maintained in, a specific location.
3 Q24367 (/NAS) Q94543 (/NAS) Q9W2R4 (/NAS)
Asymmetric cell division GO:0008356
The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.
3 Q24367 (/TAS) Q94543 (/TAS) Q9W2R4 (/TAS)
Regulation of asymmetric cell division GO:0009786
Any process that modulates the frequency, rate or extent of asymmetric cell division.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Establishment of mitotic spindle localization GO:0040001
The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Establishment of mitotic spindle localization GO:0040001
The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
3 Q24367 (/NAS) Q94543 (/NAS) Q9W2R4 (/NAS)
Establishment of mitotic spindle localization GO:0040001
The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
3 Q24367 (/TAS) Q94543 (/TAS) Q9W2R4 (/TAS)
Asymmetric protein localization involved in cell fate determination GO:0045167
Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
3 Q24367 (/NAS) Q94543 (/NAS) Q9W2R4 (/NAS)
Asymmetric protein localization involved in cell fate determination GO:0045167
Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
3 Q24367 (/TAS) Q94543 (/TAS) Q9W2R4 (/TAS)
Basal protein localization GO:0045175
Any process in which a protein is transported to, or maintained in, basal regions of the cell.
3 Q24367 (/TAS) Q94543 (/TAS) Q9W2R4 (/TAS)
Apical protein localization GO:0045176
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Apical protein localization GO:0045176
Any process in which a protein is transported to, or maintained in, apical regions of the cell.
3 Q24367 (/IPI) Q94543 (/IPI) Q9W2R4 (/IPI)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Regulation of nervous system development GO:0051960
Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)
Asymmetric neuroblast division GO:0055059
The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
3 Q24367 (/IGI) Q94543 (/IGI) Q9W2R4 (/IGI)
Asymmetric neuroblast division GO:0055059
The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
3 Q24367 (/TAS) Q94543 (/TAS) Q9W2R4 (/TAS)
Malpighian tubule tip cell differentiation GO:0061382
The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.
3 Q24367 (/IMP) Q94543 (/IMP) Q9W2R4 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 Q24367 (/IDA) Q94543 (/IDA) Q9W2R4 (/IDA)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
3 Q24367 (/IDA) Q94543 (/IDA) Q9W2R4 (/IDA)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
3 Q24367 (/NAS) Q94543 (/NAS) Q9W2R4 (/NAS)
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
3 Q24367 (/IDA) Q94543 (/IDA) Q9W2R4 (/IDA)
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
3 Q24367 (/TAS) Q94543 (/TAS) Q9W2R4 (/TAS)