The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Leucine-rich Repeat Variant
".
FunFam 2482: Sister chromatid cohesion protein pds5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9HFF5 (/IPI) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitotic sister chromatid cohesion GO:0007064
The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
|
1 | Q9HFF5 (/IMP) |
|
Establishment of mitotic sister chromatid cohesion GO:0034087
The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.
|
1 | Q9HFF5 (/IMP) |
|
Maintenance of mitotic sister chromatid cohesion GO:0034088
The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
|
1 | Q9HFF5 (/IMP) |
|
Protein localization to kinetochore GO:0034501
Any process in which a protein is transported to, or maintained at, the kinetochore.
|
1 | Q9HFF5 (/IMP) |
|
Attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation GO:0051456
The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs.
|
1 | Q9HFF5 (/IMP) |
|
Protein localization to chromatin GO:0071168
Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
|
1 | Q9HFF5 (/IDA) |
|
Protein localization to chromosome, centromeric region GO:0071459
Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.
|
1 | Q9HFF5 (/IMP) |
|
Protein localization to nuclear pericentric heterochromatin GO:1902682
A process in which a protein is transported to, or maintained in, a location within a nuclear pericentric heterochromatin.
|
1 | Q9HFF5 (/IMP) |
|
Positive regulation of mitotic cohesin unloading GO:1905411
Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading.
|
1 | Q9HFF5 (/IDA) |
|
Negative regulation of mitotic cohesin loading GO:1905412
Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading.
|
1 | Q9HFF5 (/IDA) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear chromosome GO:0000228
A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
|
1 | Q9HFF5 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9HFF5 (/IDA) |
|
Nuclear pericentric heterochromatin GO:0031618
Nuclear heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.
|
1 | Q9HFF5 (/IDA) |
|
Wpl/Pds5 cohesin loading/unloading complex GO:0090695
A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA.
|
1 | Q9HFF5 (/EXP) |