The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Leucine-rich Repeat Variant
".
FunFam 1253: Protein CLASP-2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P32744 (/IPI) |
|
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
1 | P32744 (/ISS) |
There are 16 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Astral microtubule organization GO:0030953
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles.
|
3 | P32744 (/IGI) Q03609 (/IGI) Q95YF0 (/IGI) |
|
Establishment of mitotic spindle localization GO:0040001
The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
|
3 | P32744 (/IGI) Q03609 (/IGI) Q95YF0 (/IGI) |
|
Meiotic spindle organization GO:0000212
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.
|
1 | P32744 (/IMP) |
|
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
|
1 | P32744 (/IMP) |
|
Astral microtubule organization GO:0030953
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles.
|
1 | P32744 (/IMP) |
|
Positive regulation of microtubule depolymerization GO:0031117
Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.
|
1 | Q95YF0 (/IMP) |
|
Sister chromatid biorientation GO:0031134
The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.
|
1 | P32744 (/IMP) |
|
Establishment of mitotic spindle localization GO:0040001
The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
|
1 | P32744 (/IMP) |
|
Microtubule polymerization GO:0046785
The addition of tubulin heterodimers to one or both ends of a microtubule.
|
1 | P32744 (/IDA) |
|
Spindle elongation GO:0051231
The cell cycle process in which the distance is lengthened between poles of the spindle.
|
1 | Q95YF0 (/IGI) |
|
Mitotic spindle midzone assembly GO:0051256
The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.
|
1 | P32744 (/IMP) |
|
Meiotic spindle midzone assembly GO:0051257
The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.
|
1 | P32744 (/IMP) |
|
Mitotic sister chromatid separation GO:0051306
The process in which sister chromatids are physically detached from each other during mitosis.
|
1 | P32744 (/IMP) |
|
Meiotic chromosome separation GO:0051307
The process in which chromosomes are physically detached from each other during meiosis.
|
1 | P32744 (/IMP) |
|
Attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation GO:0051316
The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex contributing to meiotic chromosome segregation.
|
1 | P32744 (/IMP) |
|
Cytoplasmic streaming GO:0099636
The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains.
|
1 | P32744 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
1 | P32744 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P32744 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P32744 (/IDA) |
|
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | P32744 (/IDA) |
|
Spindle midzone GO:0051233
The area in the center of the spindle where the spindle microtubules from opposite poles overlap.
|
1 | P32744 (/IDA) |
|
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
|
1 | P32744 (/IDA) |