The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 123: Importin 9

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
13 Q96P70 (/IPI) Q96P70 (/IPI) Q96P70 (/IPI) Q96P70 (/IPI) Q96P70 (/IPI) Q96P70 (/IPI) Q96P70 (/IPI) Q96P70 (/IPI) Q96P70 (/IPI) Q96P70 (/IPI)
(3 more)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
13 Q96P70 (/ISS) Q96P70 (/ISS) Q96P70 (/ISS) Q96P70 (/ISS) Q96P70 (/ISS) Q96P70 (/ISS) Q96P70 (/ISS) Q96P70 (/ISS) Q96P70 (/ISS) Q96P70 (/ISS)
(3 more)
Nuclear import signal receptor activity GO:0061608
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
13 Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA)
(3 more)
Ran GTPase binding GO:0008536
Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.
1 Q91YE6 (/TAS)
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
1 Q91YE6 (/IDA)
Nuclear import signal receptor activity GO:0061608
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
1 Q91YE6 (/ISO)
Nuclear import signal receptor activity GO:0061608
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
1 Q91YE6 (/ISS)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
14 Q91YE6 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA)
(4 more)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
1 Q91YE6 (/IMP)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
1 Q91YE6 (/ISA)
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
1 Q91YE6 (/ISO)
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
1 Q91YE6 (/ISA)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
1 Q91YE6 (/ISA)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
13 Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA) Q96P70 (/IDA)
(3 more)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
13 Q96P70 (/HDA) Q96P70 (/HDA) Q96P70 (/HDA) Q96P70 (/HDA) Q96P70 (/HDA) Q96P70 (/HDA) Q96P70 (/HDA) Q96P70 (/HDA) Q96P70 (/HDA) Q96P70 (/HDA)
(3 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q91YE6 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q91YE6 (/ISS)