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CATH Superfamily 1.25.10.10

Leucine-rich Repeat Variant

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1061: Deoxyhypusine hydroxylase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
 3 D9IFD5 (/IDA) D9IFD5 (/IDA) D9IFD5 (/IDA)
Cofactor binding GO:0048037
Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
 3 D9IFD5 (/ISS) D9IFD5 (/ISS) D9IFD5 (/ISS)
Iron ion binding GO:0005506
Interacting selectively and non-covalently with iron (Fe) ions.
 1 Q4Q901 (/ISO)
Deoxyhypusine monooxygenase activity GO:0019135
Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
 1 Q4Q901 (/ISO)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Peptidyl-lysine modification to peptidyl-hypusine GO:0008612
The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
 3 D9IFD5 (/IDA) D9IFD5 (/IDA) D9IFD5 (/IDA)
Hypusine metabolic process GO:0046516
The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.
 3 D9IFD5 (/IDA) D9IFD5 (/IDA) D9IFD5 (/IDA)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
 1 Q4Q901 (/ISO)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.