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CATH Superfamily 1.20.910.10

Heme oxygenase-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Heme oxygenase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Heme oxygenase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Heme oxygenase (biliverdin-IX-beta and delta-forming). [EC: 1.14.99.58]
(1) Protoheme + 3 reduced acceptor + 3 O(2) = biliverdin-IX-delta + CO + Fe(2+) + 3 acceptor + 3 H(2)O. (2) Protoheme + 3 reduced acceptor + 3 O(2) = biliverdin-IX-beta + CO + Fe(2+) + 3 acceptor + 3 H(2)O.
  • The enzyme, characterized from the bacterium Pseudomonas aeruginosa, differs from EC 1.14.15.20 in that the heme substrate is rotated by approximately 110 degrees within the active site, resulting in cleavage at a different part of the ring.
  • It forms a mixture of about 70% biliverdin-IX-delta and 30% biliverdin-IX-beta.
 100 A0A0H2Z6D9 A0A0H2Z6D9 A0A0H2Z6D9 A0A0H2Z6D9 A0A0H2Z6D9 A0A0H2Z6D9 A0A0H2Z6D9 A0A0H2Z6D9 A0A0H2Z6D9 A0A0H2Z6D9
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